Week 2 - BCH 3.01 B-vitamins Part 1

which metablic pathways use Vitamin B1

what are the dietary sources of vitamin B1 (thiamin)? how is it digested?

how is vitamin B1 (thiamin) absorbed?

how is vitamin B1 (thiamin) transported?

how is vitamin B1 (thiamin) stored?

how is vitamin B1 (thiamin) excreted?

what are the functions of Thiamin diphosphate (TDP)?

how is TDP used to make acetyl-CoA?

• describe the enzyme used

• steps

how does the alpha-ketoglutarate dehydrogenase complex work?

what does Transketolase do? what pathway is it apart of? how does it work?

what are the 2 anti-thamine factors in food?

what are pro-thiamine factors in food?

how do vitamin B1 deficiencies occur?

compare dry beriberi and wet beriberi B1 deficiencies

describe Wernicke-Korsakoff syndrome

what kinds of medications affect thiamine

how can thiamin activity be tested?

what symptoms arise due to Vitamin B2 deficiency?

what are the dietary sources of vitamin B2 (ribflavin)

how is Vitamin B2 (riboflavin) digested?

how is Vitamin B2 (riboflavin) absorbed?

how is Vitamin B2 (riboflavin) stored?

how is Vitamin B2 (riboflavin) excreted?

what are the functions fo B2

• Reduction reactions

• supports ETC and nutrient metabolism

• nucleuic acid metabolism

• antioxidant

• vitamin metabolism

• neurotransmitters

• hydrogen peroxide

how is B2 involved in reduction reactions?

how is B2 involved in ETC support and nutrient metabolism?

how is B2 involved in Nucleic acid metabolism?

how is B2 an antioxidant

how is B2 an involved in vitamin metabolism

how is B2 involved with neurotransmitters?

how is B2 involved with hydrogen peroxide?

how is vitamin B2 levels tested

how can B2 prevent migraines? cataracts?

what are the symptoms of a B2 deficiency?

in which pathways is B2 involved in? (FAD/FADH2 or FMN/FMNH2)

what are the sources of Vitamin B3 (niacin)

how is Vitamin B3 digested?

how is Vitamin B3 absorption?

how is Vitamin B3 storaged?

how is Vitamin B3 excreted?

what is the overall function of Niacin/B3

What are the biochemical fuunctions of Niacin

what are the physiological effects of nicotinic acid

what are the physiological effects of nicotinamide

what is Vitamin B3/niacin deficiency called? symptoms? causes?

how is vitamin B3 tested?

what synmptom presentation points to B5 deficiency

what are the sources of vitamin B5 “pantos”

how is vitamin B5 digested?

describe teh structure of CoA and how B5 fits in it

how is B5 absorbed?

how is B5 stored?

how is B5 excreted?

what are the 4 processes B5 is involved in?

what are the functions on B5

what is B5 deficiency called? what are the causes?

how is B5 tested?

which B vitamins are in glycolysis

which B vitamins are in CAC

which B vitamins are in ETC

which B vitamins are in beta-oxidation

which B vitamins are in cholesterol