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ICF
intracellular fluid; consists of all the fluid enclosed within the plasma membranes of the body’s trillions of individual cells
ECF
extracellular fluid; encompasses all biophysical fluids located outside of cell membranes. It acts as a buffer zone and transport system between the external environment and the cells
plasma
the liquid component of blood found inside the cardiovascular system, accounting for about 5% to 7% of total body fluid; it acts as a delivery system to transport blood cells, nutrients, and waste products
interstitial fluid
the tissue fluid that directly bathes and surrounds the cells, making up roughly 12% to 25% of total body fluid; it allows for the constant exchange of water and solutes between the cells and the blood supply
transcellular fluid
a specialized category contained within epithelial-lined spaces, accounting for about 1% to 2.5% of extracellular fluid; cerebrospinal fluid, synovial fluid in joints, ocular fluid, and digestive juices
homeostasis
fluid and electrolytes must remain balanced; when balance is disrupted, patients can develop fluid, electrolyte, and acid-base imbalances
osmosis
a special type of diffusion that applies only to water molecules moving across a partially permeable membrane; passive
diffusion
the random movement of particles or dissolved substances from an area of high concentration to an area of low concentration; passive
active transport
the movement of particles across a cell membrane using special protein pumps (ATP); low to high concentration
isotonic
same osmolality as plasma; expands the ECF; has an equal concentration of solutes compared to the inside of the cell; water moves in and out at equal rates, so the cell volume stays stable
hypertonic
higher osmolality than plasma; pulls water toward the ECF; has a higher concentration of solutes than the cell's interior; water rushes out of the cell, causing it to shrink or shrivel
hypotonic
lower osmolality than plasma; has a lower concentration of solutes than the cell's interior; water moves into the cell, causing it to swell or potentially burst
hypotonic IV fluids
0.45% NaCl (1/2 NS) - half of normal saline - GIVE HYPOTONIC IV FLUIDS TO HYPERTONIC PATIENTS WHOSE CELLS ARE SHRUNKEN
isotonic IV fluids
0.9 NaCl (NS), Lactated Ringer’s (LR)
fluid volume deficit
not enough fluid in the body/circulation
fluid volume excess
too much fluid in the body/circulation
hypovolemia
a fluid deficit inside the intravascular compartment (the blood vessels); short on blood volume
hypovolemia causes
diarrhea, drainage, hemorrhage, polyuria, inadequate intake, fluid shifting out of the vascular space
hypovolemia findings
tachycardia, weakness, postural hypotension, dehydration
hypervolemia
fluid volume excess/overload; too much fluid inside the blood vessels (the intravascular compartment)
hypervolemia causes
excess fluid intake, heart failure, renal failure, fluid shifting into the vascular space
hypervolemia findings
weight gain, peripheral edema, increased blood pressure, JVD, bounding pulse, crackles, shortness of breath, orthopnea
edema
palpable swelling; expansion of interstitial fluid volume which can hold an additional 10-30 L of fluid
edema assessment
daily weight, measurements, finger pressure, visual assessment
edema treatment
underlying cause; elevate diuretic therapy
fluid volume overload (overhydration)
0+: no pitting edema; 1+: 2 mm or less (mild; immediate rebound); 2+: 3-4 mm (moderate; 15 seconds rebound); 3+: 5-6 mm (moderately severe; 30 seconds to rebound); 4+: 8 mm or deeper (severe; 1-2 minutes to rebound)
1st fluid spacing
fluid is where it normally belongs
2nd fluid spacing
fluid moves into the tissues —> edema
3rd fluid spacing
fluid gets trapped where the body can’t easily use it
hypokalemia
low potassium
hyperkalemia
high potassium
hyponatremia
low sodium
hypernatremia
high sodium
hypocalcemia
low calcium
hypercalcemia
high calcium
hypomagnesemia
low magnesium
hypermagnesemia
high magnesium
normal serum electrolyte ranges: sodium
136 - 145 mEq/L
normal serum electrolyte ranges: potassium
3.5 - 5.0 mEq/L
normal serum electrolyte ranges: calcium
8.5 - 10.5 mg/dL
normal serum electrolyte ranges: magnesium
1.5 - 2.5 mEq/L