Immunology- Blood groups and immunity

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Last updated 11:08 PM on 7/22/26
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9 Terms

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Alloantibodies

  • naturally occurring antibodies

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Dog blood types

  • Over a dozen but major groups are:

    • DEA 1

    • DEA 3

    • DEA 4

    • DEA 5

    • DEA 7

  • DEA: dog erythrocyte antigen

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Dog blood transfusions

  • DEA 1 elicits the strongest antigen response and causes more transfusion complications

  • approx. 50% of dogs are positive for DEA 1

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Cat blood types

  • A, B, or AB

  • very few cats have AB blood, most U.S cats have A blood

  • Type B may be found in purebreds and geographical areas like Australia

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Horses blood types

More than 30 types

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Tube method blood typing

  • requires antisera (antibodies specific for each possible blood type of a given species)

  • Not practical for large animal blood typing

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Card agglutination blood typing

  • rapid and accuarate blood typing

  • there is a positive control which will agglutinate to show test works and then the test with the patient blood and DEA 1 compound to show if patient blood reacts

<ul><li><p>rapid and accuarate blood typing</p></li><li><p>there is a positive control which will agglutinate to show test works and then the test with the patient blood and DEA 1 compound to show if patient blood reacts </p></li></ul><p></p>
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Immunochromatographic assay

  • control band detects separate antigens on RBCs

<ul><li><p>control band detects separate antigens on RBCs</p></li></ul><p></p>
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Crossmatching

  • can be done if antisera is unavailable

  • two types: Major and minor crossmatching

  • Major- Few drops of serum from recipient are added to a few drops of prewashed pRBCs (packed red blood cells = plasma removed RBCs)

  • Minor- A few drops of serum from donor are mixed with washed pRBCs from recipient