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What is hyperemesis gravidarum?
Severe, excessive nausea and vomiting during pregnancy
Leads to weight loss, dehydration, electrolyte imbalance, nutritional deficiencies, and ketonuria
Caused by elevated estrogen, progesterone, and hCG levels
What differentiates normal morning sickness from hyperemesis gravidarum?
Morning sickness: mild, limited to early pregnancy
Hyperemesis: persistent, severe, interferes with nutrition and fluid intake, causes ketonuria and electrolyte imbalance
What are the key assessment findings for a client with hyperemesis gravidarum?
Weight loss and dehydration
Dry mucous membranes and poor skin turgor
Decreased BP, increased pulse
Irritability, tearfulness, mood changes
What laboratory findings are expected in hyperemesis gravidarum?
Hypokalemia, hyponatremia, ketonuria, bilirubinemia, and decreased total protein
Electrolyte imbalances: ↓Na⁺, ↓K⁺, ↑BUN/Cr if dehydrated
Positive ketones in urine from starvation ketosis
May have metabolic alkalosis from prolonged vomiting
What are normal reference ranges for key labs to monitor?
Hgb: 12–16 g/dL
Hct: 37–47%
WBC: 5,000–10,000/mm³
BUN: 10–20 mg/dL
Creatinine: 0.5–1.1 mg/dL
Albumin: 3.5–5 g/dL
Bilirubin: 0.1–1.2 mg/dL
Blood pH: 7.35–7.45
What are the primary problems of concern in hyperemesis gravidarum?
Electrolyte imbalance
Decreased fluid volume
Undernutrition
Anxiety
What is the initial nursing intervention for a client with severe hyperemesis?
Insert IV catheter
Begin IV therapy for fluid and electrolyte correction
NPO initially, then small frequent meals as tolerated
What medications are used to manage hyperemesis gravidarum?
Vitamin B6 (pyridoxine) or pyridoxine + doxylamine (Diclegis)
Antiemetics:
Promethazine (Phenergan)
Ondansetron (Zofran)
Acid reducers:
Antacids, H2 blockers, proton pump inhibitors (PPIs)
IV fluids or TPN if oral intake not tolerated
What nursing interventions support comfort and recovery?
Provide a quiet, odor-free environment
Monitor urine ketones daily
Monitor I&O and weight
Oral care after vomiting
Offer small, frequent meals (bland, dry, salty, or sweet)
Monitor for metabolic acidosis signs
What should a nurse do if a pregnant client calls reporting vomiting for 5 days?
Instruct her to come in immediately to clinic or ER
The severity cannot be determined safely by phone
What alternative or complementary remedies may help nausea in pregnancy?
Ginger (tea, warm ginger ale)
Peppermint or raspberry leaf tea
Acupressure wristbands (SeaBands)
What teaching should nurses provide to manage nausea/vomiting at home?
Eat dry, starchy foods (toast, crackers) before rising in morning
Eat small, frequent meals every 2–3 hrs
Avoid skipping meals or getting too hungry
Eat high-protein snacks at bedtime
Avoid strong odors and fatty/spicy foods
Drink fluids between meals, not during
Avoid brushing teeth immediately after eating
Try cool foods with low aroma
Get fresh air or open windows for ventilation
Suck on lemon slices or try salty/tart foods (chips, lemonade)
Get up slowly from bed to prevent nausea
What discharge teaching is important for ongoing management?
Monitor weight and urine output daily
Report no improvement, signs of dehydration, or persistent vomiting
Emphasize rest, hydration, and nutrition
Follow-up visits to reassess labs and fetal growth
What indicates effective treatment of hyperemesis gravidarum?
Client tolerates oral fluids
Stable weight or weight gain
Normal electrolyte values
No ketones in urine
Improved mood and energy