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what are the worst case scenarios of ACS using the acronym TAP MAP
tension pneumothorax, ACS, pulmonary embolism, mediastinitis, aortic dissection, pericardial tamponade
pathophysiology of coronary artery disease?
a narrowing and stiffening of the arteries that perfuse the myocardium. It is caused by atherosclerosis. this causes an imbalance in oxygen supply and oxygen demand.
other names for coronary artery disease
heart disease or coronary heart disease
name some risk factors for ACS and an acronym to help
HTN, age, male
CHAM FOLDS is an acronym you can use.
define ischaemia
restricted blood flow to a part of the body
define injury in the context of ACS
tissue has suffered damage due to ischaemia. if reperfused it can heal.
define infarction
myocardial death due to prolonged ischaemia
define stable angina
reproduced by exercise, eating and stress and is relieved with rest and without recent change in frequency or severity of activity that produce symptoms
what is needed to diagnose acute myocardial infarction?
clinical presentation, ECG findings and biomarkers (we don't have these in the field yet).
what does STEMI stand for?
ST segment elevated myocardial infarction
what is cardiogenic shock?
primary cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion
characteristics of ACS pain
radiating, be diffuse and not pinpoint, non aggravating and non relieving, feels like a previous cardiac episode.
pharmacology of aspirin
causes irreversible inhibition of cyclooxygenase necessary for thromboxane A2 synthesis which is responsible for platelet aggregation and vasoconstriction
common dose for aspirin
300mg
common dose for GTN spray
400mcg
what is the pharmacology of GTN
promotes vascular smooth muscle relaxation which causes venous and arterial dilation reducing preload and afterload
this reduces oxygen demand, systolic diastolic and MAP, provides coronary artery dilation
true or false, electrical activity within the heart can only ever begin at the SA node or AV node
false
the PR interval is measured from the...
end of the p wave to the end of the QRS
when a sinus rhythm has a QRS complex of 0.12seconds or greater this is an abnormality called
aberrant conduction or wide QRS
what occurs during diastole?
relaxation and filling
what occurs during systole?
contraction and blood ejection
how long does the cardiac cycle last?
0.8 seconds
What is cardiac output?
amount of blood pumped by each side of the heart in one minute
Cardiac output formula
heart rate multiplied by stroke volume
what is stroke volume
the volume of blood pumped by each ventricle in one contraction
what electrolytes are mainly involved with electrophysiology?
sodium and potassium
what does sodium and potassium do with regards to electrophysiology?
the movement of these electrolytes causes changes to electrical balance causing an electrical current to form
what role does calcium play in electrophysiology?
after depolarisation occurs calcium enters cells to allow for mechanical contraction of the heart
what is the rate of the SA node?
60-100bpm
what is rate of the AV node?
40-60bpm
what is the rate of the ventricles?
20-40 bpm
define automaticity
cells in the heart generating their own electrical activity
where does the sympathetic nervous system affect the heart?
atria, junction and ventricles
how does the sympathetic nervous system affect the heart?
increase HR, increase conduction velocity, increase contractility, increase irritability
what parts of the heart do parasympathetic nervous system affect?
atria
how does the parasympathetic nervous system affect the heart?
slow the atrial firing rate, slow conduction, decrease contractility, decrease irritability
what nerve is part of the parasympathetic nervous system?
vagus nerve
what happens when the vagus nerve is stimulated
it can slow the atrial firing rate, slow conduction, decrease contractility, decrease irritability
name the four pacemaker sites
sinus, atrial, junctional and ventricular
what number must I remember for the 300 method for calculating the rate of an ECG strip?
300, 150, 100, 75, 60, 50, 43, 38, 33
what defines an atrial rhythm?
abnormal p waves
what defines junctional rhythms?
inverted the p waves/short PR interval due to retrograde depolarization
what indicates ventricular rhythms?
wide QRS complexes
what is a sinus dysrhythmia
irregular pattern but still a sinus rhythm
name two types of supraventricular tachycardia
atrioventricular nodal reentrant tachycardia (AVNRT) or atrioventricular re-entry tachycardia (AVRT)
how does chronotropy impact cardiac conduction?
increase heart rate
how does dromotrophy impact cardiac conduction?
increase conduction velocity
how does inotropy impact cardiac conduction?
increase contractility
define contractility
describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload and preload
define irritability
a state of increased sensitivity to stimuli
how do atrial p waves present?
flat, notched, peaked, saw-toothed and di-phasic
name three causes for variant angina
1. prinzmetal's angina
2. arterial dissection
3. secondary causes e.g. fever, anemia etc.
what is an aortic dissection
a split in the media of the aortic wall
what causes an aortic dissection?
high pressure caused by blood movement from the contraction of the heart
what are some ways to recognise aortic dissection?
ripping or tearing pain radiating through to back, sudden onset, different blood pressures in the arms
what is a pulmonary embolism
the lodging of a clot in the pulmonary arteries.
how do you recognise a pulmonary embolism?
sharp, locased chest pain, aggravated by breathing, unexplained SOB, poor SpO2, hemoptysis , signs and risk factors for DVT, no adventitious sounds on auscultation
what is a tension pneumothorax
the presence of air in the pleural space - a collpased lung
how do you recognise a tension pneumothorax
chest pain on affected side, pain aggravated by inspiration, decreased breath sounds on effective side, trauma, JVD and tracheal deviation, subcutaneous emphysema (gas bubbles under skin), hypotensive, ALOC
what is pericardial tamponade
accumulation of fluid in the pericardial sac
what happens to the ventricles in pericardial tamponade?
fluid impedes ventricular filling leading to decreased CO
how do you recognise pericardial tamponade?
chest pain relieved/aggravated with lean and lay test, hypotension, JVD and muffled heart sounds, fever, history of trauma
what are the three elements of the beck triad
hypotension, JVD, muffled heart sounds.
what is mediastinitis
a life threatening infection of the mediastinum
what is the likely cause of mediastinitis
thoracic surgery and esophageal rupture from persistent vomiting
how to recognise mediastinitis
signs of sepsis, fever, constant vomiting, recent chest surgery
what is costochondritis
inflammation of the costochondral junctions where the ribs meet the sternum
signs of costochondritis
localised pain, aggravated by palpation, sharp and pleuritic, pain changes with position coughing and inspiration, due to overuse or trauma
what is reflux
reflux of gastric contents back into the esophagus
signs of reflux
burning, radiating up neck, epigastric region, due to large meals sometimes, nausea, regurgitation or burping, relieved by antacids
define anxiety
a psychological disorder that can often present with chest pain and hyperventilation
what are some signs of anxiety
acute onset, pleuritic chest pain, SOB, trembling, shaking, altered sensation, distressed and anxious
what muscles could be responsible for chest pain?
intercostal muscles and the pectoris major
what are some signs of muscular chest pain?
localised, sharp in nature, aggravated by movement, palpation, coughing, inspiration, caused by trauma/exertion
what is pneumonia
infection and inflammation of the lung parenchyma resulting in impaired gas exchange
what are some signs of pneumonia
localised chest pain, pleuritic, productive cough, fever, SOB with coarse crackles
what is pleurisy
inflammation of tissues that line the lungs and chest cavity (parietal and visceral). this makes the two layers rub together. caused by an underlying bacterial or viral condition
what are some signs of pleurisy?
acute onset, localised to side, pleuritic in nature, friction rub heard on auscultation, fever, shoulder pain
what is pericarditis
inflammation of the pericardium, the membrane that surrounds the heart
what are some signs of pericarditis?
sharp, pleuritic pain, aggravated by laying back and relieved by sitting up, global ECG changes, fever
what can pericarditis lead to ?
cardiac tamponade
what is pancreatitis
inflammation of the pancreas often associated with excessive alcohol
signs of pancreatitis
severe epigastric pain that can radiate to chest and back, aggravated on palpation of the epigastric region, alcohol consumption, N/V, fever
what is oesophageal spasm
chest pain associated with the spasming and contracting of the oesophagus
signs of oesophageal spasm
sudden chest pain, feeling of choking, difficulty swallowing, occurs after eating
what is shingles
a virus that can cause painful rash over the skin
what are some signs of shingles
pain along dermatomes, paresthesia, rash evident
are first degree heart blocks regular or irregular?
regular mostly - depends on the underlying rhythm
are 2nd degree type 1 heart blocks regular or irregular?
irregular
are 2nd degree type 2 heart blocks regular or irregular?
irregular
are 3rd degree heart blocks regular or irregular?
regular
what is an acronym that is used for other ACS differentials?
CRAMPPPSS
what does the CRAMPPPSS stand for?
costochondritis, reflux, anxiety, muscular, pulmonary (infection/inflammation), pericarditis, pancreatitis, spasm of the esophagus, skin
what is shock?
failure of the circulatory system to adequately provide oxygen to organs and the peripheral tissue.
how does the body attempt to maintain perfusion status
CO= HR x SV
what factors result in hypoperfusion
blood flow, blood volume, peripheral resistance
define cardiogenic shock
inadequate CO
define distributive shock
loss of vasomotor resistance in arterioles and venules
give two examples of distributive shock
anaphylaxis and sepsis
define obstructive shock
from impedance to flow in major vessels