Contracts in arteries to maintain blood flow and pressure as blood moves further away from the heart.
New cards
2
Tunica intima
Innermost layer in veins and arteries, made up of a single endothelium layer and has elastic fibres in the collagen which can stretch and recoil.
New cards
3
Tunica media
Contains elastic fibres and smooth muscle, and is thicker in arteries than veins, to maintain high blood pressure.
New cards
4
Elastic fibres
Stretch to accomodate for changes in blood flow and pressure caused by the heart pumping too fast or slow. At a certain point they recoil to push blood through the artery.
New cards
5
Tunica externa
Outermost layer of veins and arteries, contains collagen fibres to resist overstreching, which prevents blood cells bursting. Withstands very high pressures.
New cards
6
Open
Type of circulatory system where the blood is not moved around in vessels, but bathes the tissues directly while held in a cavity.
New cards
7
Haemocoel
Cavity where blood is held in open circulatory systems.
New cards
8
Closed
Type of circulatory system where blood is moved in blood vessels. There are two types, single and double.
New cards
9
Single
Type of closed circulation, where blood moves around the heart once in it’s passage of the body.
New cards
10
Dorsal
Top of an animal such as earthworms, for example a type of fin and vessel.
New cards
11
Ventral
Bottom of an animal such as earthworms, for example a type of vessel.
New cards
12
Pseudohearts
Thickened, muscular blood vessels which pump the blood from dorsal to ventral vessels in earthworms.
New cards
13
Double
Type of closed circulation where blood passes through the heart twice in it’s circuit around the body.
New cards
14
Atrium
Part of the heart where blood enters, has less muscle and thinner walls.
New cards
15
Ventricle
Part of the heart where blood leaves, has more muscle and thicker walls.
New cards
16
Left
Side of the heart where oxygenated blood leaves and is pumped around the body, has a thicker and more muscular ventricle.
New cards
17
Right
Side of the heart where deoxyginated blood enters and is pumped towards the lungs.
New cards
18
Pulmonary
Type of circulation that moves from the heart, to the lungs, and back to the heart.
New cards
19
Systematic
Type of circulation that moves from the heart, to the bodily tissues, back to the heart.
New cards
20
Arteries
Carry blood away from the heart, are larger, with less lumen and more tunica externa and media. Vary from 160-120mmHg of blood pressure.
New cards
21
Veins
Carry blood back to the heart, are smaller, with more lumen and less tunice externa and media. Have semi-lunar valves to prevent flow to feet. Around 10mmHg of blood pressure
New cards
22
Capillaries
A vast network which penetrates all tissues and organs of the body, where exchange of materials takes place. From 30mmHg-15mmHg of blood pressure.
New cards
23
Arterioles
Branch off from arteries, and further branch into capillaries. Around 33mmHg of blood pressure.
New cards
24
Venules
Where blood from capillaries collects, takes blood into veins. Around 15mmHg of blood pressure.
New cards
25
Semi-lunar
Valves present in veins, prevent gravity from pushing blood down the body. Also present in the heart, to prevent blood pumped from the ventricle into the pulmonary artery or aorta does not fall back. Open when the heart pumps, and close to stop backflow.
New cards
26
Endothelium
Part of tunica intima in arteries and veins, but alone on capillaries. Lines the vessels, one cell thick. Smooth to prevent friction.
New cards
27
Lumen
Where blood flows, cavity in the vessels.
New cards
28
Tricuspid
A valve on the right side of the heart between the atrium and the ventricle. Closes once pressure in the ventricle is higher than in the atrium.
New cards
29
Bicuspid
A valve on the left side of the heart between the atrium and the ventricle. Closes once pressure in the ventricle is higher than in the atrium.
New cards
30
Myogenic
Type of contraction where contraction and relaxation happen rhythmically and without outside intervention. Used by the human heart.
New cards
31
Atrial systole
Occurs at 0.1 seconds, when atrial walls contract, pushing blood into the ventricles.
New cards
32
Atrial diastole
Occurs at 0.2, once the atrium relaxes, blood begins to enter again via vena cavae and the pulmonary veins.
New cards
33
Ventricular systole
Occurs at 0.2 seconds, when ventricle walls contract and the atrio-ventricular valves close, blood is pushed into the pulmonary artery or aorta and the semi-lunar valves open.
New cards
34
Ventricular diastole
Occurs at 0.4 seconds, when the ventricles relax, semi-lunar valves shut and the atrio-ventricular valves close.
New cards
35
Sinoatrial node
Group of specialised cardiac cells that produce an electrical impulse, located in the wall of the right atrium.
New cards
36
Atrioventricular node
Pases down the SAN impulse to the ventricles, as they are electrically insulated by a thin layer of connective tissue. Allows for a delay between atria and ventricles contracting.
New cards
37
His bundle
Passed the electrical impulse by the AVN, and then pass it down to the left and right bundle branches.
New cards
38
Apex
Part of the heart that recieves the AVN impulse from the left and right His bundle branches and then transports it to the Purkinje fibres.
New cards
39
Purkinje fibres
Inside the ventricle walls, pass the electrical impulse up the ventrical wall muscles to cause the ventricles to contract simultaneously.
New cards
40
Atrio-ventricular valves
Term for the bicuspid and tricuspid valves.
New cards
41
Electrocardiogram
Trace of the voltage changes during a heartbeat, detecting by placing electrodes on the skin.
New cards
42
P wave
Part of electrocardiogram that shows voltage generated by the SAN for atria contraction.
New cards
43
PR interval
Part of a cardiogram that shows the time taken for the voltage from the SAN to reach the AVN.
New cards
44
QRS complex
Part of the electrocardiogram that shows the contraction of the ventricles.
New cards
45
T wave
Part of the electrocardiogram that shows the repolarisation of the ventricle.
New cards
46
Isoelectric line
Line between the T wave and the next P wave of the next heartbeat that shows the baseline of the trace.
New cards
47
Erthrocytes
Word for red blood cells.
New cards
48
Biconcave discs
The shape of red blood cells, allows for a smaller diffusion pathway of oxygen and larger SA.
New cards
49
Haemoglobin
Red pigment in blood that carries oxygen. Takes up around 95% of red blood cell mass. Has two beta chains, and two alpha chains.
New cards
50
Plasma
Pale yellow, the liquid part of blood that is made up of 90% water. It contains amino acids, urea and the red of the blood cells.
New cards
51
Haem
Part of the haemoglobin that contains an iron ion and join to one oxygen molecule. As there are four in haemoglobin, allows it to carry four oxygen molecules.
New cards
52
Oxyhaemoglobin
Complex created when four oxygens bind to haemoglobin.
New cards
53
Cooperative binding
Process in which haemoglobin changes it’s shape to make it easier for oxygen to bond. Happens after the first and second oxygen bond, meaning the fourth requires a large increase in oxygen concentration.
New cards
54
Dissociate
Term for when oxygen unbinds with haemoglobin, happens in respiring tissues.
New cards
55
High affinity
Happens to haemoglobin in lower oxygen conditions - attaches to an increased amount of oxygen but releases a decreased amount. Left shift on a dissociation curve.
New cards
56
Low affinity
Happens to haemoglobin in higher oxygen conditions - attaches to an decreased amount of oxygen but releases a increased amount. Right shift on a dissociation curve.
New cards
57
Myoglobin
In muscles for oxygen storage. Globular tertiary protein with only one haem group.
New cards
58
Dissociation curve
Graph that shows the higher oxygen concentration, the higher concentration of oxygen in haemoglobin. Includes oxygen concentration in exercising tissues, resting tissues and the lung alveoli.
New cards
59
Bohr
Effect that shows that areas of high carbon dioxide concentration oxygen is dissociated easier, for example in the capillaries.
New cards
60
Carbamino-haemoglobin
How 10% of carbon dioxide travels.
New cards
61
5
How much carbon dioxide travels as a solution in the plasma.
New cards
62
HCO3-
How 85% of carbon dioxide travels.
New cards
63
Carbonic anhydrase
Enzyme that catalyses the combination of carbon dioxide and water into carbonic acid.
New cards
64
Carbonic acid (H2CO3)
Created by the combination of carbon dioxide and water in a red blood cell.
New cards
65
Chloride ions (Cl-)
Diffuse into a cell to maintain electrochemical neutrality when HCO3- ions leave.
New cards
66
Chloride shift
The movement of chloride ions into a red blood cells to maintain electrochemical neutrality when HCO3- ions leave.
New cards
67
Haemoglobic acid (HHb)
Caused by the dissociation of oxyhaemoglobin by H+ ions, which then combine with haemoglobin.
New cards
68
Tissue fluid
Plasma without the collodial plasma proteins, carries molecules to allow them to diffuse into the tissues and carries waste products back into the blood.
New cards
69
Collodial plasma proteins
In plasma to reduce solute potential, too large to leave via ultra-filtration.
New cards
70
Ultra-filtration
Procces where substances are pushed out from the blood, such as oxygen, glucose, amino acids, etc, into tissue fluid, allowing cells to absorb them.
New cards
71
Absorption
Process where waste products are diffused into tissue fluid from cells, such as urea and carbon dioxide.
New cards
72
10
Amount of tissue fluid that doesn’t return to the blood and drains into the lymph capillaries.
New cards
73
Venous system
Term for the network of veins around the body.
New cards
74
Thoracic duct
Where the 10% of tissue fluid left behind returns to the venous system, where it then empties into the subclavian vein above the heart.
New cards
75
Hypertension
When blood pressure is too high, causing build up of waste products and carbon dioxide known as oedema.
New cards
76
Hypotension
When blood pressure is too low, causing cells to go without important nutrients and blood volume to increase.
New cards
77
Oedema
Build up of waste materials and carbon dioxide caused by hypertension. Causes swelling in feet.
New cards
78
Sigmoidal
Word for an S shaped curve - such as a dissociation curve. Allows for rapid unloading of oxygen at small oxygen partial pressure changes.