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Multiple Sclerosis
Degeneration of the myelin sheath, resulting in slowed or blocked nerve impulses
Multiple Sclerosis Etiology
The cause of multiple sclerosis is unknown, but it is believed to be related to an autoimmune response or viral infection
Multiple Sclerosis Signs and Symptoms
Muscle weakness, numbness, fatigue, slurred speech, vision disturbances, vertigo, ataxia, dysphagia, bowel/bladder problems, sexual dysfunction, and mood alterations
Multiple Sclerosis Additional Manifestations
The disease may have periods of remission and exacerbation, which can be triggered by stress or illness. Immobility is common, and death is usually caused by infection
Multiple Sclerosis Diagnostic Tests
Diagnosis is based on a history and physical examination, cerebrospinal fluid (CSF) analysis, and magnetic resonance imaging (MRI)
Multiple Sclerosis Therapeutic Interventions
Treatment options include steroids, interferon therapy, immunosuppressant agents, anticonvulsants, muscle relaxants, plasmapheresis, and physical/occupational/speech therapies
Myasthenia Gravis
An autoimmune disorder where antibodies destroy acetylcholine receptors, resulting in a loss of voluntary muscle strength
Myasthenia Gravis Etiology
The cause of myasthenia gravis is unknown, but it is believed to be related to an autoimmune or viral origin, as well as thymus disorders
Myasthenia Gravis Signs and Symptoms
Progressive muscle weakness, fatigue with activity, ptosis (drooping of the eyelids), difficulty chewing/swallowing/breathing, and periods of remission and exacerbation, which can be triggered by stress
Myasthenia Gravis Complications
Complications of myasthenia gravis include aspiration, respiratory infection and failure, myasthenic crisis, cholinergic crisis, and SLUDGE (salivation, lacrimation, urination, defecation, gastrointestinal upset, and emesis)
Myasthenia Gravis Diagnostic Tests
Diagnosis is based on a history and physical examination, Tensilon test, anti-acetylcholine receptor antibodies, and electromyography (EMG)
Myasthenia Gravis Therapeutic Interventions
Treatment options include thymectomy (removal of the thymus), anticholinesterase agents, steroids, and plasmapheresis
Myasthenia Gravis Nursing Process
Nursing care focuses on managing activity intolerance, teaching energy conservation techniques, infection prevention, recognizing signs and symptoms of crisis, medication avoidance education, and providing support group resources
Amyotrophic Lateral Sclerosis (ALS)
A progressive neurodegenerative disease where motor neurons degenerate, leading to muscle weakness and atrophy
ALS Etiology
The cause of ALS is unknown, but there may be a genetic predisposition
ALS Signs and Symptoms
Progressive muscle weakness and atrophy, decreased coordination, muscle spasm, difficulty chewing/swallowing, emotional lability, speech difficulty, pulmonary compromise, and death due to pulmonary complications
ALS Diagnostic Tests
Diagnosis is based on a history and physical examination, lumbar puncture with cerebrospinal fluid (CSF) analysis, electroencephalogram, nerve biopsy, and electromyography (EMG)
ALS Therapeutic Interventions
Treatment options include muscle relaxants, Riluzole (Rilutek), physical/occupational/speech therapies, pain control, enteral feedings, infection prevention, and augmentative alternative communication
Guillain-Barre Syndrome
An inflammatory disorder that affects the spinal and cranial nerves, causing ascending demyelination and descending remyelination
Guillain-Barre Syndrome Etiology
The cause of Guillain-Barre syndrome is unknown, but it is believed to be related to an autoimmune response triggered by a viral infection
Guillain-Barre Syndrome Signs and Symptoms
Stage 1: Abrupt onset of weakness and paralysis, which may affect respiration and the autonomic nervous system. Stage 2: Plateau phase, where the progression of symptoms stops. Stage 3: Recovery phase, where improvement occurs
Guillain-Barre Syndrome Complications
Complications of Guillain-Barre syndrome include respiratory failure, infection, depression, pneumonia, urinary tract infection, and complications related to immobility
Guillain-Barre Syndrome Diagnostic Tests
Diagnosis is based on lumbar puncture with cerebrospinal fluid (CSF) analysis, electromyography (EMG), nerve conduction velocity tests, and pulmonary function testing
Guillain-Barre Syndrome Therapeutic Interventions
Treatment options include plasmapheresis, oxygen therapy, mechanical ventilation, emotional support, and rehabilitation
Postpolio Syndrome
A condition that affects individuals who previously had polio, causing muscle weakness, fatigue, pain, and respiratory compromise. Treatment involves rest and symptom management
Nursing Diagnoses for Neuromuscular Disorders
Common nursing diagnoses for neuromuscular disorders include ineffective airway clearance, impaired physical mobility, imbalanced nutrition, and impaired verbal communication
Cranial Nerve Disorders
Conditions affecting the cranial nerves, such as trigeminal neuropathy and Bell's palsy
Trigeminal Neuralgia
A condition characterized by irritation of the trigeminal nerve, resulting in intense pain on one side of the face triggered by touch, talking, or stimulation
Trigeminal Neuralgia Diagnostic Tests
Diagnosis is based on a history and physical examination, computed tomography (CT) scan, and magnetic resonance imaging (MRI)
Trigeminal Neuralgia Therapeutic Interventions
Treatment options include anticonvulsants, nerve blocks, and surgery to block pain signals
Bell's Palsy
An inflammatory condition that causes inflammation and edema of the facial nerve, resulting in a loss of motor control
Bell's Palsy Signs and Symptoms
One-sided facial pain, weakness, speech difficulty, drooling, tearing of the eye, and inability to blink
Bell's Palsy Diagnostic Tests
Diagnosis is based on a history and physical examination, electromyography (EMG), and ruling out a stroke
Bell's Palsy Therapeutic Interventions
Treatment options include prednisone, analgesics, antiviral medication, moist heat, gentle massage, and a facial sling for support
Nursing Diagnoses for Cranial Nerve Disorders
Common nursing diagnoses for cranial nerve disorders include acute pain, imbalanced nutrition, and the risk for injury to the eyes (in the case of Bell's palsy)