weak/strong nucleophiles and bases

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Chemistry

Organic Chemistry

Last updated 1:30 AM on 11/20/22

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1

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weak base, weak nucleophile

water, ROH

2

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weak base, strong nucleophile

Cl-, Br-, I- (halogens)
CN- (cyanide)
N3- (azide)
N3-
CH3COO- (acetate ion)
RSH

*these are all fairly small!!

3

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strong base, strong nucleophile

OH- (hydroxide)
NH2- (amine)
-OR

4

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strong base, weak nucleophile

tBuO- (tert-butoxide)
DBU
DBN