Hormones and other Endocrine Drugs

Estradiol cypionate

Estrogen - ECP

IM

Used to induce estrus in mares (equine)

Diethylstilbestrol (DES)

Estrogen

PO

Used to treat estrogen-responsive urinary incontinence and other conditions in dogs and cats

Toxic to bone marrow, DO NOT USE when pregnant, BANNED in food animals

Megestrol

Progestin - Ovaban, Megace

PO

For false pregnancy, control of estrus cycle

DO NOT USE while pregnant, cna induce hypoadrenocorticism, personality changes, transient diabetes, and other possible side effects

Altrenogest

Progestin - Regu-Mate

PO

Used primarily in horses to synchronize estrus or maintain pregnancy, many handling warnings

Medroxyprogesterone

Progestin - Depo-Provera, Provera, Cycrin

IM, SQ, PO

Used in treatment of some behavioral and dermatologic conditions, many side effects

Testosterone

Androgen

IM, SQ

C-III with limited use in veterinary medicine

Mibolerone

Androgen - Cheque Drops

PO

Prevention of estrus and treatment of pseudocyesis in adult dogs

Not recommended for cats, controlled substance

Dinoprost

Prostaglandin - Lutalyse

SQ

Primarily used for estrus synchronization in cattle, may also cause abortion

Pregnant women and people with asthma should handle only with EXTREME caution

Fluprostenol/Cloprestenol

Prostaglandin - Equimate

SQ

LA use, induce luteolysis (breaks down corpus luteum)

Desmopressin

Pituitary hormone - DDAVP, Stimate

SQ, intranasal

ADH used in control of diabetes insipidus and an aid for von Willebrands disease

Oxytocin

Pituitary hormone - Pitocin

IV, IM, SQ

Induction or enhancement of uterine contractions at parturition

Vasopressin

Pituitary hormone - Pitressin

IM (diagnostic), IV (CPR)

Hormones used in dx and tx of diabetes insipidus

Can also be used in refractory shock and in CPR and as vasoconstrictor for BP support, lowkey expensive and rarely carried in vet med

Fludrocortisone

Steroid - Florinef

PO

Mineralocorticoid used for tx of hypoadrenocorticism

Desoxycorticosterone (DOCP)

Steroid - Percorten-V, Zycotral

IM

Mineralocorticoid used for tx of hypoadrenocorticism

Mitotane, trilostane

Steroid inhibitors - Lysodren, Vetoryl

PO

For tx of pituitary-dependent hyperadrenocorticism

Selegiline (L-deprenyl)

Anipryl, Eldepryl

PO

For tx of hyperadrenocorticism, also used in tx of canine cognitive dysfunction

Insulin

Antidiabetics

SQ, IM, IV (Regular insulin ONLY)

Store in refrigerator, mix GENLY, clients should be given thorough instructions on the use of insulin

Glipizide, glyburide

Glucocorticoids, Micronase, DiaBeta

PO

Oral anti diabetic agents,, useful in cats for NON-INSULIN dependent diabetes mellitus

Levothyroxine

Drugs affecting thyroid hormone - Soloxine, Thyrozine, Thyroid=Tabs

PO

T4 thyroid hormone supplement

Liothyronine

Drugs affecting thyroid hormone - Cytobin, Cytomel, Triostat

PO

T3 hormone supplement, may be useful in hypothyroid cases that do not respond to T4

Methimazole

Drugs affecting thyroid hormone - Tapazole, Felimazole

PO

Used in medical management of feline hyperthyroidism