Blood Bank Lec. 3 Nature of Antigens

0.0(0)
Studied by 0 people
call kaiCall Kai
Locked
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/16

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 12:35 AM on 9/1/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai
Chat

No analytics yet

Send a link to your students to track their progress

17 Terms

1
New cards

What are some factors that INFLUENCE the immune response?

  1. Age

  2. Overall Health

  3. Route of Exposure

  4. Genetic Capacity (DNA)


2
New cards

What happens if there is TOO LITTLE antigen present?

MAY NOT be enough to activate the ADAPTIVE immune system

3
New cards

What happens at the APPROPRIATE AMOUNT of antigen?

The immune response MOST LIKELY to be triggered

4
New cards

What happens if you have TOO MUCH antigen?

  • TOLERANCE

    • Immune system becomes less responsive to the antigen


5
New cards

What is an antigen?

An antigen is going to be a FOREIGN body that can be RECOGNIZED by the immune system

6
New cards

What is an immunogen?

AN ANTIGEN that triggers an immune response

7
New cards

What is important for an antigen to be an IMMUNOGEN

  1. Appropriately FOREIGN to the body

    1. MORE FOREIGN = more success

  2. LARGE ENOUGH to be recognized

  3. Chemically complex enough (PROTEINS)

EFFECTIVE immunogen

8
New cards

Why is it important for a immunogen to be large?

Must be large to be RECOGNIZED by the

9
New cards

Why is a more complex immunogen more successful?

Immunogen such as PROTEINS are more difficult to destroy

1, 2, 3, 4 structure

10
New cards

What is an Epitope?

  • RECOGNIZABLE PART of an immunogen

  • Recognized by the lymphocytes


11
New cards

What are the two conformations of EPITOPE?

  1. Linear

    1. linear chain of amino acids

  2. Conformational

    1. Distant amino acid groups joining together


<ol><li><p>Linear</p><ol><li><p>linear chain of amino acids </p></li></ol></li><li><p>Conformational </p><ol><li><p>Distant amino acid groups joining together</p></li></ol></li></ol><p></p>
12
New cards

What are Haptens?

  • SMALL ANTIGENS that typically DONT produce an immune response byself

  • ATTACH (hop) to another larger molecule, triggering an immune response


<ul><li><p>SMALL ANTIGENS that typically DONT produce an immune response byself</p></li><li><p>ATTACH (hop) to another larger molecule, triggering an immune response </p></li></ul><p></p>
13
New cards

What are Adjuvants (ayudame)

  • Substances that ENHANCE immune response

    • utilized in VACCINATIONS

  • Keeps antigen in site where other immune cells can pull up STRONGER REACTION


14
New cards

What is an AUTOANTIGEN

Antigens WITHIN self

DO NOT trigger an immune response

  • If immune response triggered on autoantigens = AUTOIMMUNE DISEASES


15
New cards

What is an ALLOANTIGEN?

Antien from SAME SPECIES different individual

  • MAY trigger immune response


16
New cards

What is a HETEROANTIGEN?

Antigen from a DIFFERENT SPECIES

  • Typical immune response activators

  • Bacterial antigen, animal, plant


17
New cards

What is HETEROPHILE ANTIGEN?

Antigen from DIFFERENT SPECIES BUT have the SAME STRUCTURE

Cause SIMILAR immune responses