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kidney
organ that regulates body fluid
men
gender that is made of a higher percentage of water
decreases
what happens to water content in your body as you age
75
percent of muscle that is water
fat
type of tissue that has more water
60
percent of total body weight that is water
intracellular fluid
location of 2/3 of total body fluid
extracellular fluid
1/3 of total body fluid
plasma and interstitial fluid
2 compartments of extracellular fluid
nonelectrolytes
don’t carry electrical charge when dissolved, most are carbon based
electrolytes
have an electrical charge and most are inorganic
electrolytes
body fluids with greater osmotic power
osmotic power
ability to cause water movement
osmolarity
total solute concentration in solution
osmosis
movement of water from low to high osmolarity
power
degree of solute concentration to cause osmosis
tonicity
capability of a solution to modify the volume of cells by altering their water content
electrolytes
most abundant solutes in the body
Sodium
major cation in ECF
Chlorine
major anion in ECF
Potassium
major cation in ICF
hydrogen phosphate
major anion in ICF
hypotonic
water moves inside, higher osmolarity in cell
hypertonic
water leaves cells, high osmolarity outside cell
isotonic
equal concentrations
0.9
percent of salt in the body in order to be isotonic
hypothalamus
regulator of thirst
increased sodium concentration
trigger for release of ADH
ADH
primary hormone responsible for tonicity homeostasis
sodium
only cation that exerts significant osmotic pressure
sodium
water follows ________
renin-angiotensin-aldosterone mechanism
responsible for regulation of sodium balance
decreased sodium concentration/decreased BP
trigger for kidneys to secrete renin
adrenal
glands that release aldosterone hormone
sodium reabsorption
effect of aldosterone hormone
ANP: atrial natriuretic peptide
released by heart and inhibits ADH, renin, and aldosterone
decreases sodium ion and water absorption, reduces blood volume and blood pressure
effects of ANP
lowers
effect of ANP on blood pressure
potassium
chemical that affects resting membrane potential
hyperkalemia
elevated potassium levels
hypokalemia
decreased potassium levels
nephron
location of potassium regulation
hypercalcemia
calcium problem that is common in pregnancy
parathyroid
hormone that is responsible for the majority of calcium regulation
raises blood calcium
effect of parathyroid hormone
osteoclasts
part of the bone that is stimulated by PTH
promotes reabsorption
role of PTH in the kidney
promotes calcium absorption
role of PTH in small intestine
lowers blood calcium
effect of calcitonin
thyroid
gland that releases calcitonin
osteoblasts
part of the bone stimulated by calcitonin
inhibits absorption
role of calcitonin in the kidneys and small intestine
7.4
normal arterial blood pH
7.35
normal venous blood pH
pyruvic acid
bodily acid produced as a normal byproduct of metabolism
kidneys and cardiorespiratory system
2 organ systems that remove acids
chemical buffer systems, brain stem respiratory centers, and renal mechanisms
3 mechanisms that regulate the concentration of hydrogen ions
binds proton
action of chemical buffer when pH drops
release proton
action of buffer when pH rises
bicarbonate buffer system
buffer system that regulates ECF
kidney
organ that regulates bicarbonate
respiratory system
organ system that regulates carbon dioxide
increased
effect of higher CO2 levels in blood on respiratory rate
phosphate buffer system
buffer system responsible for regulation of ICF
renal buffer
most long term and important buffer system
collecting duct
location of renal buffer
renal buffer
buffer system responsible for eliminating the other acids produced by cellular metabolism
type A intercalated cells
cells that are activated by acidosis and get rid of H+, usually more active
type B intercalated cells
cells that are activated by alkalosis and reabsorb H+
medulla oblongata
part of the brain stem that controls respiratory system
respiratory acidosis/alkalosis
acid-base abnormalities caused by CO2 levels
metabolic acidosis/alkalosis
acid-base abnormalities caused by anything other than CO2 levels, often abnormal bicarbonate levels