Prefrontal Cortex Divisions

Dorsolateral Function

Monitors and adjusts behavior using working memory and executive functions

Dorsolateral lesions

executive function deficit; disinterest/emotional reactivity; decreased attention to relevant stimuli

Ventrolateral function

response inhibition; goal appropriate response selection; attentional control; vigilance

Ventrolateral lesions

emotional dysregulation; poor attention & vigilance

Orbitofrontal function

personality, emotional input, social behavior, suppression of distracting signals

Orbitofrontal lesions

emotional lability; distractibility; social inappropriateness

Dorsomedial function

arousal, motivation, initiation of activity

Dorsomedial lesions

apathy, decreased drive/awareness, akinetic-abulic syndrome, mutism

Ventromedial function

emotional control, empathy

Ventromedial lesions

impaired judgement, inappropriate social behavior