Anti-coagulants quiz

MOA heparin? use?

Prevents clots by activating antithrombin, use: stroke, PE, DVT, prophylaxis, DIC

What meds are contradicted when taking heparin?

NSAIDS and ASA

What are normal PTT times?

60-70 seconds

What are normal aPTT times?

20-35 seconds

How is enoxaparin administer (low molecular weight heparin)

prefilled syringes do not expel bubbles, not monitored, subcutaneous rotate sites.

What is the therapeutic range of clotting times to see effectiveness in heparin?

1-2x patients base line ex. 60sec therapeutic 90-120 seconds

What med is considered high-risk anticoagulant?

hepari

Adverse effects of dabigatron (direct thrombin inhibitor)? Interventions?

Gi upset: take with food & PPI or H2, bleeding hemrrohage.

What clotting labs are monitored when taking warfarin ( vitmain K inhibitor?)

Pt and INR times. normal PT: 11-12.5 sec INR: .78-1.1 sec

Therapuetic ranges of PT and INR?

PT: 18-24 sec, INR:2-3 sec

Complications of alteplase (thrombolytics)? and interventions?

Increased risk of bleeding, pregnancy and lactating,

What is the reversal agent of Alteplase (thrombolytics)?

amiocaproic

possible complications of Aspirin?

Gi upset, hemorrhage stroke, prolonged bleeding, tinnitus (hearing loss)!

What do you need to know before administering alteplase?

weight because its based on dosing, monitor LOC, VS, weakness.