2.1 DNA Replication, Transcription and Translation

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Vocabulary flashcards covering key concepts related to DNA replication and transcription.

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19 Terms

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Nucleus

The cell organelle responsible for information storage, housing DNA.

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DNA Replication

The process by which a cell duplicates its DNA before cell division.

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Central Dogma

The flow of genetic information from DNA to RNA to protein.

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Transcription

The process of synthesizing RNA from a DNA template.

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Translation

The process of synthesizing proteins from mRNA at ribosomes.

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mRNA

Messenger RNA that conveys genetic information from DNA to the ribosome.

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tRNA

Transfer RNA that carries amino acids to the ribosome for protein synthesis.

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rRNA

Ribosomal RNA that forms the core of ribosome's structure and catalyzes protein synthesis.

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DNA polymerase

The enzyme responsible for synthesizing new DNA strands during replication.

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Ligase

The enzyme that joins Okazaki fragments to form a unified DNA strand.

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Okazaki fragments

Short segments of DNA synthesized on the lagging strand during replication.

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Exonuclease

An enzyme that removes RNA primers during DNA replication.

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Mismatch repair

A DNA repair process that fixes incorrectly paired bases.

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Homologous recombination

A DNA repair mechanism that uses an undamaged homologous chromosome as a template.

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Nucleotide excision repair

A DNA repair process that removes and replaces damaged nucleotides.

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Amino acid

The building blocks of proteins, encoded by mRNA during translation.

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Gene activation

The process of uncoiling DNA to expose a gene sequence for transcription.

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5’ cap

A modified guanine nucleotide added to the 5’ end of mRNA for protection and initiation of translation.

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Poly(A) tail

A sequence of adenine nucleotides added to the 3’ end of mRNA that aids in export and stability.