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Nerves
Collection of thousands of axons of neurons
Ganglion
Collection of cells bodies of neurons in PNS
Inferior end of spinal cord
Conus medullaris
Spinal cord spans from….
Medulla oblongata to inferior border of L1 vertebrae
Cervical enlargment
Neurons → upper extremity
Lumbosacral enlargment
Neurons → lower extremity
Spinal cord white matter is
myelinated axons
What do myelinated axons do, and where do we find them
they relay nerve signals, and in the white matter of the spinal cord
Spinal cord grey matter
Dendrites and cell bodies of neurons
The grey matter of the spinal cord is the
process center
Posterior median
sulcus
Anterior median
fissure
Dorsal/Posterior root ganglion
cell bodies of sensory neurons
Dorsal/Posterior root
Axons of sensory neurons
Ventral/Anterior root
Axons of motor neurons
Spinal nerves
merger of ventral and dorsal roots, mixed nerves
Cervical region
C1-C8
Thoracic Region
T1-T12
Lumbar region
L1-L5
Sacral Region
S1-S5
Coccygeal Region
Co1
How many vertebrae in the Cervical region
8
How many vertebrae in the Thoracic Region
12
How many vertebrae in the Lumbar region
5
How many vertebrae in the Sacral Region
5
How many vertebrae in the Coccygeal Region
1
Cauda equina
Nerve roots of inferior spinal nerves L2-Co1
Posterior ramus
small branch, innervates muscles and skin of back
Anterior ramus
Splits into multiple other branches, many involved plexuses
Rami communicantes
Small branches of autonomic fibers
Spinal nerve → sympathetic trunk ganglion
Sympathetic trunk ganglia
ganglia of sympathetic neurons
Dermatomes
part of skin with only one spinal nerve
What are dermatomes involved in
referred visceral pain
pain from one organ is mistakenly
referred to a dermatome
What spinal nerve roots contribute to the intercostal nerves?
Ventral rami of T2–T11
What areas do the intercostal nerves innervate?
Muscles of the ribs, anterolateral thorax, and abdominal wall
What is a nerve plexus?
A network of interweaving ventral rami of spinal nerves
Where are nerve plexuses found?
In the cervical, brachial, lumbar, and sacral regions
What do nerve plexuses primarily serve?
The limbs
What does each nerve contain?
Axons from several ventral rami
How is each limb muscle supplied with nerves?
By more than one spinal nerve
What forms the cervical plexus?
Ventral rami of C1 - C4
What does the phrenic nerve innervate?
Diaphragm
What spinal nerves form the cervical plexus?
Ventral rami of C1–C4
What important nerve comes from the cervical plexus?
Phrenic nerve
What does the phrenic nerve innervate?
The diaphragm
What spinal nerves form the brachial plexus?
Ventral rami of C5–T1 (often also C4 and T2)
How many major nerves innervate the upper limb from the brachial plexus?
Five
What muscle does the axillary nerve innervate?
Deltoid
The five nerves that innervate the upper limb
Musculocutaneous n
Median n
Axillary n
Radial n
Ulnar n
What muscle does the musculocutaneous nerve innervate?
Biceps brachii, brachialis
What nerve passes through the carpal tunnel?
Median nerve
What does the median nerve innervate?
Some flexors of the wrist and fingers
What does the ulnar nerve innervate?
Some anterior forearm muscles
What does the radial nerve innervate?
Triceps brachii, brachioradialis, and extensors of the wrist and fingers
What spinal nerves form the lumbar plexus?
Ventral rami of L1–L4
What does the lumbar plexus innervate?
The thigh, abdominal wall, and psoas muscle
What does the femoral nerve innervate?
Quadriceps femoris and sartorius
What does the obturator nerve innervate?
Adductor group and gracilis
What spinal nerves form the sacral plexus?
Ventral rami of L4–S4
What does the sacral plexus serve?
The buttock, lower limb, pelvic structures, and perineum
What is the longest and thickest nerve of the body?
Sciatic nerve
Where does the sciatic nerve split?
Superior to the popliteal fossa
What two nerves does the sciatic nerve split into?
Tibial nerve and fibular nerve
What muscles are innervated by the tibial nerve?
Biceps femoris long head, semimembranosus, semitendinosus, soleus, gastrocnemius
What muscles are innervated by the fibular nerve?
Short head of biceps femoris and tibialis anterior
What is the major nerve of the cervical plexus?
Phrenic nerve
What muscle does it innervate?
Diaphragm
List the ventral rami that make up the brachial plexus
C5–T1 (often also C4 and T2)
List the rami that make up the lumbar plexus
L1–L4
List the nerves that make up the sacral plexus
L4–S4
What is “rami”
branches of a spinal nerve
What structures protect the spinal cord?
Bone (vertebrae), meninges, and cerebrospinal fluid (CSF)
What are meninges?
Connective tissue membranes covering the brain and spinal cord
What is the filum terminale?
A thin strand of pia mater that anchors the conus medullaris to the coccyx
Put the spinal cord structures in order from superficial to deep:
Vertebrae
Epidural space
Dura mater
Subdural space
Arachnoid mater
Subarachnoid space
Pia mater
Deepest structure in the spinal cord?
Pia mater
Most superficial structure in the spinal cord?
Vertebrae
Where are lateral horns found in the spinal cord?
Only in segments T1–L2
What do lateral horns contain?
Cell bodies of autonomic motor neurons
What do autonomic motor nuclei innervate?
Smooth muscle, heart, and glands
What do the posterior/dorsal horns of the spinal cord contain?
Axons of sensory neurons and cell bodies of interneurons
What type of nuclei are found in the dorsal horns?
Sensory nuclei
What do somatic sensory nuclei receive signals from?
Skin, muscles, and joints
What do visceral sensory nuclei receive signals from?
Blood, vessels, and viscera
What is the gray commissure?
Gray matter with unmyelinated axons that connect the left and right gray matter
What structure runs through the center of the gray commissure?
Central canal
What are tracts in the spinal cord?
Bundles of axons in white matter
What do ascending tracts carry?
Sensory signals from receptors to the spinal cord to the brain
What do descending tracts carry?
Motor signals from the brain to the spinal cord to effectors
What type of information does the posterior funiculus carry?
Sensory/ascending
What type of information does the lateral funiculus carry?
Sensory/ascending and motor/descending
What type of information does the anterior funiculus carry?
Mostly motor/descending
What are three characteristics of conduction pathways?
They are paired, most decussate (cross over), and each is made of a chain of two or more neurons
What does decussation in conduction pathways result in?
Contralateral control (opposite side of the body)
Where are axons located in conduction pathways?
In spinal cord tracts (white matter)
Where are cell bodies located in conduction pathways?
Ganglia, spinal cord gray horns, and brain gray matter
What do somatosensory pathways carry signals for?
Proprioception, touch, temperature, pressure, and pain
Where do somatosensory pathways start?
At a sensory receptor
How many neurons are in somatosensory pathways?
Up to 3 neuron chain