Postmortem Toxicology

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Flashcards focused on vocabulary related to Postmortem Toxicology.

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16 Terms

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Toxicology

The study of the effects of substances on living organisms.

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Postmortem Toxicology

Analysis of biological samples after death to determine substances present.

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Branches of Toxicology

Various types of toxicology including analytical, applied, clinical, forensic, environmental, reproductive and developmental, and immuno-toxicology.

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Xenobiotic

Substances that are foreign to the body.

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Drug

A compound that causes a physiological effect.

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Poison

A substance that, when ingested, results in a toxic or damaging physiological response.

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Marsh Test

A test for detecting arsenic that involves a chemical reaction to produce arsine gas.

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First Pass Effect

The hepatic metabolism of a drug when absorbed from the gut and delivered to the liver, reducing its bioavailability.

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ADME

Acronym for Absorption, Distribution, Metabolism, and Excretion of drugs in the body.

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Dose

The amount of a substance taken that can be therapeutic or toxic.

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Curtailment of Toxicity Factors

Factors contributing to the toxicity of a substance include mode of ingestion and individual metabolism.

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Degree of toxicity

Determined by factors such as biological effects, mode of ingestion, and body weight.

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Carfentanil

A potent synthetic opioid where just a few micrograms can be deadly.

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Opiates

Natural derivatives from the opium plant that can cause physiological effects, with potential for overdose.

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Fentanyl

A synthetic opioid that is significantly more potent than heroin and is involved in rising overdose rates.

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Body Fluids For Toxicology

Common specimens for toxicological analysis include blood, urine, liver, and vitreous humor.