cytochrome P450 substrate properties
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5 Terms
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CYP 1A2 substrates
planar, moderately basic, medium volume
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CYP 2C9
weakly acidic, lipophilic, 1-2 H bond donor/acceptor
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CYP 2C19
neutral or weakly basic, 2-3 H bond donors/acceptors
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CYP 2D6
basic, relatively hydrophilic, H bond donor/acceptor
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CYP 3A
high volume, lipophilic, structurally diverse, 1-2 H bond donors/acceptors
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Chapter Fifteen: Treatments for Schizophrenia and Other Severe Mental Disorders
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