the development of t lymphocytes
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14 Terms
thymocytes
immature t cells
purpose of macrophage in medulla and cortex of thymus
get rid of immature t cells that fail to mature properly
what kinds of cells in thymus
know diagram which one points to what
thymocytes
cortical epithelial cells
what replaces t cell producing tissue throughout life
fatty tissue
why does replacement of t cell producing tissue not impair immunity
mature peripheral t cells self-renew or long-lived
immunosenescence
gradual reduction of immunocompetence with age
what happens when the uncommitted progenitor cell enters thymus after a week
loose stem cell markers
committed thymocytes to t cell lineage
after, rearrange t cell receptor genes
why is the committed thymocyte double negative
don’t express cd4 or cd8 yet