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Scrotum
Skin-covered muscular sac that extends from the body and encloses the testes, controlling temperature for sperm development
Dartos muscle
Smooth muscle that gives the scrotum a wrinkled appearance; contracts in cold (decreases skin surface area) and relaxes in heat
Cremaster muscle
Muscle in the scrotum that reflexively contracts to elevate the testes in cold or relaxes to lower the testes in heat
Spermatic cord
Bundle of fibers and tissues that run through the abdominal region down to each testicle to provide blood flow, lymphatic drainage, and a conduit for the vas deferens
Pampiniform plexus
Network of small veins in the spermatic cord that surround the testicular artery and cool the blood before it reaches the testes; plays a crucial role in testicular thermoregulation
Tunica vaginalis
Outer serous membrane of the testes
Tunica albuginea
Tough, white, dense connective tissue layer covering the testes that forms septa in them to divide them into lobules
Sertoli/nurse cells
Large, branching support cells that secrete signaling molecules to promote sperm production, create the blood-testis barrier, digests excess cytoplasm of developing sperm cells, and secretes testicular fluid into the lumen of the seminiferous tubule
Blood-testis barrier
Physical barrier created via tight junctions of Sertoli cells that prevents bloodborne substances from reaching germ cells and prevents germ cells from reaching the blood and prompting an immune response
Seminiferous tubule
Developing sperm cells around a lumen that comprise the bulk of each testis
Straight tubule
Where seminiferous tubules empty
Rete testes
Fine meshwork of tubules that straight tubules empty into
Efferent ductules
Tubes that bring testicular fluid from the rete testes to the epididymis
Leydig cell
Cell in the interstitial tissues between seminiferous tubules that produce testosterone
Gubernaculum
Connective tissue fiber that contracts to move the testes through the inguinal canal to the scrotum at around month 7 of fetal development
Cryptorchidism
Condition where one or both testes fail to descend into the scrotum prior to birth; testes will not produce sperm and this condition increases the risk of testicular cancer if not surgically treated
Spermatogonia
Germ/stem cells of the testes that line the basement membrane inside seminiferous tubules
Spermatogenesis
Process that turns spermatogonia into mature sperm cells
Epididymis
Highly coiled tube next to the testes where immotile sperm mature and are stored until ejaculation
Acrosome
Cap that covers most of the head of a sperm cell and is filled with lysosomal enzymes important for breaking apart the female egg during fertilization
Ductus/vas deferens
Thick, muscular tube in the spermatic cord that brings sperm from the epididymis up to the abdominal cavity and then to the ejaculatory duct