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Sterilization
The complete destruction or removal of all microorganisms, including spores and viruses.
Sepsis
A life-threatening systemic response to infection that can lead to tissue damage, organ failure, and death.
Portal of Entry
The way a pathogen enters the body (e.g., mouth, nose, broken skin, mucous membranes).
Mode of Transmission
How a pathogen is spread from one host to another (direct contact, indirect contact, droplet, airborne, vector-borne).
Endogenous
Originating from within the body.
Opportunistic
A microorganism that causes disease when the immune system is weakened.
Reservoir
The place where a pathogen lives, grows, and multiplies (humans, animals, environment).
Standard Precautions
Infection-control practices used with all patients to prevent disease transmission (hand hygiene, PPE, safe injection practices).
PPE (Personal Protective Equipment)
Equipment worn to protect against infection (gloves, gowns, masks, face shields, goggles).
Nosocomial
Infections acquired in a healthcare setting (hospital-acquired infections).
Prions
Infectious protein particles that cause fatal brain diseases (e.g., Creutzfeldt-Jakob disease).
Disinfectant
A chemical used on non-living objects to destroy microorganisms (not spores).
Aerobic
Requiring oxygen to live and grow.
Viruses
Non-living pathogens that require a host cell to reproduce.
Aseptic
Free from contamination; preventing the presence of microorganisms.
Microorganisms
Microscopic living organisms, including bacteria, viruses, fungi, and protozoa.
Protozoa
Single-celled organisms that can cause disease.
Pathogen
A disease-causing microorganism.
Portal of Exit
The path by which a pathogen leaves its reservoir.
Correct Order to Don PPE
Gown, Mask or Respirator, Goggles or Face Shield, Gloves.
Correct Order to Doff PPE
Gloves, Goggles or Face Shield, Gown, Mask or Respirator.