Exam 1 - Weight Management

what are some health risks associated with being overweight

T2D, high BP, Heart Ds, stroke, fatty liver, cancer

what are some causes of obesity

genetics, family reinforcement, physiological factors, psychologic factors, environmental factors

how is a metabolic synrome diagnosed

at least 3 of the following:

waist circumference: >40in men, >35in women

TGs: >150mg/dl

HD:L

t/f

taking a medication for one of the listed conditions constitutes an ABN finding when diagnosing metabolic syndrome

true

what are some effects of excessive lipids

lipotoxicity - accumulation in non-adipose tisse causing ER stress, inflammation, mitochondrial dysfxn, cell death

lipid peroxidation - PUFA peroxides form due to COX, LOX, cytochrome P450s

what impacts do lipotoxicity and lipid peroxidation have on the body

pancreas, heart, kidney, liver, muscles

alter membrane structure, trigger inflammation, cancer, neurodegeneration

what are the components of a sound weight management program

dietary modifications

changing food behavior

activity

what are the steps for weight loss according to clinical practice guidelines

1. recognize obesity as chronic disease, obtain patient permission

2. assess

3. discuss tx options

4. agree on goals of therapy

5. follow-up and advocacy

how does orlistat work

pancreatic lipase inhibitor to decrease fat absorption

how do qsymia and Contrave work

appetite supressors

how do Wegovy and Saxenda work

incretin-mimics to work as appetite suppressant

what is recommended energy intake for me and women trying to lose weight

1200-1500 women

1500-1800 men

what % of energy intake should be carbs during weight loss

45-65%

non-starchy veggies, fruits, whole grains

what % of energy intake should be fat

20-35%

limit saturated and trans fats

what is the most common weight loss surgery in the US

vertical sleeve gastrectomy

what screening questionnaire is used for eating disorders

SCOFF

sick, control, one, fat, food