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What is pepsinogen?
An inactive enzyme (zymogen) is secreted by chief cells in gastric gland
Which cells secrete pepsinogen in the stomach?
Chief Cells
How is pepsin formed from pepsinogen?
Hydrochloric acid removes some amino acids to form pepsin
What is meant by the “autocatalytic effect” of pepsin?
Pepsin converts more pepsinogen into pepsin
What is the main function of pepsin?
digest dietary proteins into shorter peptide chains
Where is protein digestion completed?
Small Intestine
Which cells produce gastric lipase?
Chief cells
What role does gastric lipase play in fat digestion?
It plays a minor role in fat digestion
Approximately what percentage of dietary fats are digested in the stomach by gastric lipase?
10%-15%
Where does the partial digestion of proteins and starch/fats begin?
In the mouth and the stomach
Where does most digestion and nearly all absorption occur after chyme has passed?
Small Intestine
How much nutrient absorption occurs in the stomach?
Does not absorb any significant amount of nutrients