hypersensitivity reactions

hypersensitivity

an exaggerated or inappropriate immune response against an antigen that results in host tissue damage

It can either by self-antigen or foreign-antigen

4 types

type I immediete hypersensitivity

type II antibody-mediated diseases

Type III immune response complex-mediated diseases

These are all mediated from antibodies

Type IV T cell-mediated diseases

this is mediated from T cells

Types of hypersensitivity

Type I immediate hypersensitivity

Classic symptoms resulting from allergic responses- anaphylaxis. Includes: Hay fever, asthma, eczema, bee stings, foot allergies

lifetime prevalence of 15-30% in children and 2-10% in adults

allergic rhinitis: most common form of non-infectious rhinitis, affecting 10-30% of adults and up to 40% of children

prevalence of peanut allergy in children of western countries have doubled in the past 10 years