Cell Cycle & DNA Replication

DNA Helicase

An enzyme that unwinds the DNA double helix during DNA replication

DNA Polymerase

Enzyme involved in DNA replication that joins individual nucleotides to produce a DNA molecule

DNA ligase

enzyme that joins DNA lagging strand fragments together

Leading Strand

synthesized continuously

Lagging strand

discontinuously synthesized; made of Okazaki fragments

Interphase

nuclear replication

Cytokinesis

cytoplasmic division

Mitosis

nuclear division

Prophase

Chromosomes become visible, nuclear envelop dissolves, spindle forms

Metaphase

Chromosomes line up in the middle of the cell

Anaphase

Phase of mitosis in which the chromosomes separate and move to opposite ends of the cell

Telophase

chromosomes uncoil into chromatin; nuclear envelope re-forms