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What does plasma do?
transports all of your blood cells (+other substances) around body
What does plasma transport?
C02 - produced by cells and carried to lungs
urea - formed in liver = break down of excess proteins - moved to kidneys --> removed from blood --> urine
small soluble products of digestion --> small intestine --> plasma --> individual cells
Function of red blood cells?
carries oxygen form lungs and carries to cells where it's needed
Adaptations of red blood cells + how it works - discs
biconcave discs - increased surface area to volume ratio - diffusion
Adaptations of red blood cells + how it works - ha
have haemoglobin - red pigment that binds to oxygen
Adaptations of red blood cells + how it works - nuc
no nucleus - more space for haemoglobin
What is the route of the red blood cells
alveolus of lungs --> red blood cell --> body organ -->
Describe a white blood cell
have a nucleus, form parts of the body's defence system
Function: lymphocytes
form antibodies against microorganisms
Function of white blood cells
form antitoxins against poisons
Function: phagocytes
Engulf and digest invading bacteria + viruses
Describe platelets - what they are + structure
small frangments of cells, have no nucleus
Function: platelets
helps blood to clot at site of wound
What is blood clotting
a series of enzyme controlled reactions - converting fibrinogen to fibrin, produces network of protein fibres which captures lots of red blood cells + platelets (dries to form scab)
Function: scab
protects new skin as it grows and stops bacteria entering body (through wound)
percentage of plasma in blood
55%
percentage of cells + platelets in blood
percentage of red blood cells in blood
45%
Where is oxygen transported from + to and why?
lungs --> respiring cells Purpose: aerobic respiration
Where is C02 transported from + to and why?
Respiring cells --> lungs Purpose: waste - excreted
Where is urea transported from + to and why?
Liver --> Kidney, purpose: excess amino acids excreted
Where is amino acids transported from + to and why?
Small I. --> Cells - purpose: makes protein, small i. --> liver - purpose: broken down --> urea
Where is soluble products of digestion transported from + to and why?
Small I. --> cells - purpose: respiration + growth
Function: capillaries
where exchange of substances between the blood and tissue occurs
Function: arteries
oxygenated blood - heart --> organs (away from heart)
Function: vein
deoxygenated blood - organs --> heart (into heart)
Lumen size: capillaries
tiny vessel with narrow lumen
Lumen size: arteries
small lumen
Lumen size: veins
large lumen
Wall thickness: capillaries
a single layer thick to allow diffusion
Wall thickness: arteries
thick walls - support during high pressure
Wall thickness: veins
relatively thin walls
Muscle: capillaries
no muscle or elastic tissue
Muscle: arteries
thick layer of muscle and elastic fibres to withstand high blood pressure
Muscle: veins
thinner layers of muscle and elastic because blood is at lower pressure
Extra info: capillaries
Lots of them - provides a huge surface area for the exchange of substances
Extra info: arteries
walls can stretch and recoil to keep up/ support pressure
Extra info: veins
often have valves to prevent backflow of blood
What is double circulation
Circulation of blood from heart to lungs is separate from circulation from heart to the rest of the body
What animals have double circulation
humans and other mammals
Where does the pulmonary circulation carry blood from/to
heart (deoxygenated) --> lungs --> (oxygenated) heart
Where does the systemic circulation carry blood from/to
heart (oxygenated) --> organ --> (deoxygenated) heart
Path of pulmonary circulation
Right of heart --> pulmonary artery --> lungs --> capillaries --> pulmonary veins --> left heart
Path of systemic circulation
Left of heart --> aorta --> body/organs/respiring tissue --> vena cava (vein) --> right of heart
Why is double circulation used?
Blood passes throught the heart twice so that after it's oxygenated, it can be pumped quickly at a high pressure to the tissues to enable a high metabolic rate/activity
Double circulation route
Right atrium --> right ventricle --> pulmonary artery --> lungs --> pulmonary vein --> left atrium --> left ventricle --> aorta --> body --> vena cava --> right atrium
What happens with cardiovascular disease
Fatty material builds up in the lining of coronary artery (which is narry) and reduces blood flow to heart muscle. Heart muscle runs out of oxygen --> pain/possibly cell death/heart attacks
What do stents do
solution to cv disease, allows blood to flow freely, pushes the fats to the side
Advantages of stents
minor surgery, lets blood flow freely, can be placed almost anywhere in the body, only need local anaesthetic - person can be conscious
Negatives of stents
could block up another place, expensive
How does coronary artery bypass surgery do/work?
solution for cv disease, replaces the blocked coronary artery with bits of veins from other parts of the body
Advantages of coronary artery bypass surgery
can be use anywhere
Disadvantages of coronary artery bypass surgery
possibility of infection, risk of a stroke or heart attack during or after the surgery due to complications like blood clots.
How do statins do/work?
A group of drugs which reduce blood cholesterol levels and this slows down rate of fatty deposits
Advantages of statins
Brings down blood cholesterol, no surgery, slows down fatty deposits
Disadvantages of statins
Drugs can have side effects
Describe leaky valves
Heart valves can weaken and leak --> breathless and death if really bad
Function: heart valves
keeps the blood flowing in the right direction
Advantages of mechanical valves
Solution for leaky valves, cheaper than biological, lasts a long time (20-30 yrs)
Disadvantages of mechanical valves
have to take medicine for life - stop blood clots, major surgery
Advantages of biological valves
taken form animals e.g. pigs, lower risk of l=clots, no medication required
What is a natural pacemaker
A group of natural pacemaker cells near right atrium to keep the hart beating at a steady rhythm
What happens if the natural pacemaker stops working
Slower heartbeat --> reduces oxygen transport to muscles, too fast - blood not pumped correctly
Describe artificial pacemakers
An electrical device implanted under the skin and chest which sends electrical signals to stimulate the heart to beat properly - corrects irregularities in heart rate
Advantages of artificial pacemakers
Increases length of life, modern ones - very sensitive to body needs e.g. stimulates heart faster when exercising
Disadvantages of artificial pacemakers
Regular medical check-ups needed throughout your life
What factors affect the rate of diffusion
Short diffusion distance, large concentration gradient, large surface area, temperature (not in the body)
Alveoli Adaptations?
Short diffusion distance - one cell thick (flattened), large concentration gradient - breathing (high oxygen conc.) - flow of blood (deoxygenated), lots of alveoli
Inhalation + exhalation: intercostal muscles
Intercostal muscles contract then relax
Inhalation + exhalation: ribs
Move upwards and out then move downwards and in
Inhalation + exhalation: air
Drawn into the lungs, forced out of the lungs
Inhalation + exhalation: volume
Volume of chest increases, volume of chest decreases
Inhalation + exhalation: pressure
Pressure in chest increases, pressure inside chest decreases
Inhalation + exhalation: Diaphragm
Diaphragm contracts and flattens, diaphragm relaxes and moves upwards
Adaptations of leaves - large
Large surface area - more sunlight hitting leaf + more absorbed
Adaptations of leaves - thin
Shorter diffusion distance
Adaptations of leaves - small holes
Small holes allow gas exchange - stomata, allows CO2 in and O2 out, can lead to water loss
Adaptations of leaves - chloroplasts
Chloroplasts packed with chlorophyll - photosynthesis can take place
What is a cuticle + function?
A layer of wax that waterproofs the leaf - reducing water loss
What is a upper epidermis + function?
Thin, transparent layer that ensures that maximum amount of light reaches the photosynthesising cells
What is a palisade mesophyll + function?
The main photosynthetic layer of leaf - at top where there's most light - lots of chloroplasts to maximise light absorption
What is a spongy mesophyll + function?
Layer of loosely packed cells with many air spaces - allows easier diffusion of gases and increases the surface area
What is a xylem + function?
Hollow tubes strengthened by lignin - transports water and minerals up stem from roots to leaves
What is a phloem + function?
Tubes of living cells - very little contents which transport sugars from leaf to non-photosynthesising cells for immediate use of storage
What is a guard cells + function?
Specialised cells - able to open the stomata to allow gas exchange and close them to reduce water loss
What is a stomata + function?
Pores in leaf which allow CO2 to diffuse into the photosynthesising cells
Definition of a statin
Drugs used to lower blood cholesterol levels and improve the balance of HDLs and LDLs in the blood
Definition of pulmonary vein
Large blood vessel that carries oxygenated blood away from the lungs back to the left atrium of heart
Definition of the pulmonary artery
Large blood vessel that takes deoxygenated blood from the right ventricle of the heart to the lungs
Definition of aorta
Artery that leaves the heart from the left ventricle and carries oxygenated blood to the body
Definition of a pacemaker
A group of cells found in the right atrium of the heart that controls the basic rhythm of the heart beat
Definition of conducting fibres
Fibres which carry the electrical impuls from the pacemaker cells to the heart tissue
Definition of ventricle
Chambers of the heart that contract to force blood out of the heart
Definition of atria/atrium
Upper chambers of the heart
Definition of a heart valve
Tissue that separates 2 areas of the heart and ensure that blood flows in the right direction
Definition of the vena cava
Large vein that brings deoxygenated blood from the body to the ears
Definition of a stent
Metal mesh that is used to open up a blocked blood vessel
Definition of a coronary artery
The blood vessels that supply oxygenated blood to the heart muscle
Path of air during inhalation + exhalation
nose, trachea, bronchi, bronchioles, alveoli, O2 diffuses into capillaries, CO2 diffuses out of capillaries, alveoli (back the same way)