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The heart functions as a pump for circulating __________ in both pulmonary and systemic circulations.
blood
The heart is located in the __________ between the lungs and is enclosed in a double-walled pericardium sac.
mediastinum
The outer fibrous pericardium anchors to the __________.
diaphragm
The inner cavity of the pericardium is filled with serous membrane which secretes fluid to reduce __________ during heartbeats.
friction
The visceral pericardium directly covers the heart's surface and is continuous with the __________.
epicardium
The myocardium is composed of specialized smooth __________ muscle cells which contract rhythmically to pump blood.
cardiac
The left ventricular wall is thicker to generate the necessary pressure to pump blood throughout the __________ circulation.
systemic
The right ventricular wall is thinner and pumps deoxygenated blood to the __________ for oxygenation.
lungs
The inner layer of the heart is called __________, which lines the chambers and is composed of endothelial cells.
endocardium
Atrioventricular valves include the tricuspid and __________ valves.
mitral
The __________ prevents backflow of blood during contraction.
atrioventricular valves
The __________ is a muscular wall that separates the left and right sides of the heart.
septum
The conduction system relies on specialized cells known as __________ cells to initiate and propagate electrical impulses.
pacemaker
Desmosomes facilitate adhesion between cardiac muscle cells, ensuring synchronized __________.
contractions
Atrial contraction is represented by the __________ in an electrocardiogram.
P wave
Ventricular contraction is represented by the __________ complex in an electrocardiogram.
QRS
The __________ Node acts as a gatekeeper in the conduction system, delaying signals.
AV
The __________ lies in the right atrium and depolarizes, spreading pulse to atriums.
SA (Sino Atrial) node
The __________ of His connects the AV node to the ventricles.
AV Bundle
The cardiac control center is located in the __________ of the brain.
medulla
Baroreceptors detect blood pressure changes and send signals to the cardiac control center via __________ pathways.
sympathetic and parasympathetic
Sympathetic stimulation leads to __________ in heart rate.
increases
Parasympathetic stimulation leads to __________ in heart rate.
decreases
The left coronary artery supplies blood to the left side of the heart, including the left atrium and __________.
left ventricle
The right coronary artery supplies blood to the right side of the heart, including the __________ and right ventricle.
right atrium
Collaterals in coronary circulation are known as __________ that maintain blood flow in case of blockage.
anastomoses
In the cardiac cycle, diastole is the phase of __________ and systole is the phase of cardiac contraction.
relaxation
During diastole, increased atrial pressure opens the __________ valves and ventricles fill.
AV
When ventricles contract, pressure closes the __________ valves and atria relax.
AV
The 'lubb' sound from heart auscultation results from closure of __________ valves.
AV
The 'dupp' sound signals closure of __________ valves at the end of systole.
semilunar
Blood pressure (BP) is influenced by cardiac __________, blood volume, and peripheral resistance.
output
Cardiac output is calculated using the formula __________.
CO = SV x HR
Increased heart rate leads to increased cardiac output and can elevate __________.
blood pressure
Antidiuretic hormone (ADH) increases water reabsorption and consequently increases __________.
blood pressure
Atherosclerosis is characterized by the build-up of __________ on the artery walls.
plaque
Myocardial infarction is commonly known as a __________.
heart attack
Angina pectoris results from a deficit of __________ to meet myocardial needs.
oxygen
Ventricular fibrillation is a condition where muscle fibers conduct __________ and rapidly, potentially leading to cardiac standstill.
independently
Symptoms of congestive heart failure include shortness of breath and __________ in the lungs.
fluid accumulation
Atrial fibrillation is characterized by a heart rate over __________ beats/min.
350
SA node abnormalities can lead to __________ heart rate, which is defined as a rate less than 60 beats/min.
bradycardia
Atrial flutter typically results in an atrial heart rate of __________ beats/min.
160 to 350
Rheumatic fever may occur after an untreated __________ infection.
streptococcal