STOMACH AGENTS

Famotidine

Pepcid (OTC) — H2 receptor antagonist

Famotidine PO/Function/Common Use

PO, IV — Reduces stomach acid by blocking histamine 2 receptor — GERD, peptic ulcers

Famotidine Adverse Drug Reactions/Special Considerations

Low platelet counts (rare in most people) — Nausea, diarrhea, constipation, headache — Reduce dose in patients with poor renal function (CrCl <30 mL/min)

Dexlansoprazole

Dexilant — Proton pump inhibitor (PPI)

Dexlansoprazole PO/Function/Common Use

PO — Reduces stomach acid by blocking proton pump — GERD, peptic ulcers

Dexlansoprazole Adverse Drug Reactions/Special Considerations

Low vitamin B12, osteoporosis (long-term) — Nausea, diarrhea, constipation, headache — Take 30–60 minutes before food; only open capsules if needed and mix with applesauce

Esomeprazole

Nexium — Proton pump inhibitor (PPI)

Esomeprazole PO/Function/Common Use

PO — Reduces stomach acid by blocking proton pump — GERD, peptic ulcers

Esomeprazole Adverse Drug Reactions/Special Considerations

Low vitamin B12, osteoporosis (long-term) — Nausea, diarrhea, constipation, headache — Take 30–60 minutes before food; only open capsules if needed and mix with applesauce

Lansoprazole

Prevacid — Proton pump inhibitor (PPI)

Lansoprazole PO/Function/Common Use

PO — Reduces stomach acid by blocking proton pump — GERD, peptic ulcers

Lansoprazole Adverse Drug Reactions/Special Considerations

Low vitamin B12, osteoporosis (long-term) — Nausea, diarrhea, constipation, headache — Take 30–60 minutes before food; only open capsules if needed and mix with applesauce

Omeprazole

Prilosec — Proton pump inhibitor (PPI)

Omeprazole PO/Function/Common Use

PO — Reduces stomach acid by blocking proton pump — GERD, peptic ulcers

Omeprazole Adverse Drug Reactions/Special Considerations

Low vitamin B12, osteoporosis (long-term) — Nausea, diarrhea, constipation, headache — Take 30–60 minutes before food; only open capsules if needed and mix with applesauce

Pantoprazole

Protonix — Proton pump inhibitor (PPI)

Pantoprazole PO/Function/Common Use

PO, IV — Reduces stomach acid by blocking proton pump — GERD, peptic ulcers

Pantoprazole Adverse Drug Reactions/Special Considerations

Low vitamin B12, osteoporosis (long-term) — Nausea, diarrhea, constipation, headache — Take 30–60 minutes before food; only open capsules if needed and mix with applesauce

Sucralfate

Carafate — Cytoprotective agent

Sucralfate PO/Function/Common Use

PO — Coats the stomach surface to protect ulcers from acid — Peptic ulcer disease

Sucralfate Adverse Drug Reactions/Special Considerations

— Constipation, indigestion, nausea — Take on an empty stomach; avoid taking with other drugs