Immediate Innate Immune Responses

Q: What are the physical barriers of the body? a) Antibodies and complement proteins b) T cells and B cells c) Skin and mucosa d) Macrophages and neutrophils

Answer: c

Q: What is the role of tight junctions in epithelial tissues? a) Degrade pathogen proteins b) Disrupt pathogen membranes c) Block cell growth d) Block passage of pathogens

Answer: d

Q: What is the role of extracellular fluid flow in epithelial tissues? a) Inhibits attachment of pathogens b) Degrades pathogen proteins c) Disrupts pathogen membranes d) Blocks cell growth

Answer: a

Q: What are examples of chemical barriers in innate immunity? a) Skin and mucus b) Acid pH, antimicrobial proteins, antimicrobial peptides, and complement system c) T cells and B cells d) Antibodies and cytokines

Answer: b

Q: What does lysozyme do? a) Disrupts viral membranes b) Activates NK cells c) Digests bacterial cell wall d) Produces antibodies

Answer: c

Q: What do defensins do? a) Digest bacterial cell walls b) Activate T cells c) Produce mucus d) Disrupt bacterial and viral membranes

Answer: d

Q: What are biological barriers in epithelial tissues? a) Normal microbiota that compete for space/nutrients b) Tight junctions that block passage of pathogens c) Fatty acids that block cell growth d) Lysozyme that degrades bacterial cell wall

Answer: a

Q: How do commensal organisms benefit the host? a) Cause disease b) Aid in digestion, compete with pathogens for nutrients and space, create environment inhibitory for pathogens, help develop immune system c) Produce antibodies d) Phagocytose pathogens

Answer: b

Q: What is the role of proteases in chemical barriers? a) Degrade bacterial cell wall b) Disrupt pathogen membranes c) Degrade pathogen proteins d) Block cell growth

Answer: c

Q: What is the role of fatty acids and lactic acid in chemical barriers? a) Degrade pathogen proteins b) Degrade bacterial cell wall c) Disrupt pathogen membranes d) Block cell growth

Answer: d