Prodrugs (Not done)

0.0(0)
Studied by 0 people
call kaiCall Kai
Locked
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/22

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 10:49 PM on 7/17/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai
Chat

No analytics yet

Send a link to your students to track their progress

23 Terms

1
New cards
What is a prodrug?
A medication that must be converted in the body to its active form
2
New cards

Capecitabine is the prodrug to…

Fluorouracil (5-FU)
3
New cards

Clopidogrel is the prodrug to…

Active metabolite
4
New cards

Codeine is the prodrug to…

Morphine
5
New cards

Colistimethate is the prodrug to…

Colistin
6
New cards

Cortisone is the prodrug to…

Cortisol
7
New cards

Famciclovir is the prodrug to…

Penciclovir
8
New cards

Fosphenytoin is the prodrug to…

Phenytoin
9
New cards

Isavuconazonium sulfate is the prodrug to…

Isavuconazole
10
New cards

Levodopa is the prodrug to…

Dopamine
11
New cards

Lisdexamfetamine is the prodrug to…

Dextroamphetamine
12
New cards

Prednisone is the prodrug to…

Prednisolone
13
New cards

Primidone is the prodrug to…

Phenobarbital
14
New cards

Tramadol is the prodrug to…

Active metabolite
15
New cards

Valacyclovir is the prodrug to…

Acyclovir
16
New cards

Valganciclovir is the prodrug to…

Ganciclovir
17
New cards
Why should codeine be avoided in CYP2D6 ultra-rapid metabolizers?
Faster conversion to morphine increases toxicity risk
18
New cards
Why should codeine be avoided in CYP2D6 poor metabolizers?
Poor conversion to morphine results in inadequate analgesia
19
New cards
Which CYP enzyme activates codeine?
CYP2D6
20
New cards
Which CYP enzyme activates clopidogrel?
CYP2C19
21
New cards
Which PPIs decrease clopidogrel activation?
Omeprazole and esomeprazole
22
New cards
Why should omeprazole and esomeprazole be avoided with clopidogrel?
They inhibit CYP2C19, reducing conversion to the active metabolite and decreasing antiplatelet effect
23
New cards
What should be used instead of clopidogrel in CYP2C19 poor metabolizers?
An alternative P2Y12 inhibitor