Pain and Inflammation Pharmacotherapeutics​

Acetaminophen

Brand names: Tylenol and Ofirmev (IV form)

MOA:

• mild pain relief and fever reduction

Complications:

• Acute toxicity —> liver damage (if liver damage causes bleeding out)

Contraindications:

• if pt has sever liver or kidney impairment

• chronic alcohol use

• malnutrition

Interactions:

• alcohol

• warfarin (increases risk for bleeding)

• ANY MEDS

Nursing Implications:

• Antidote for overdose: acetylcysteine (Mucomyst)​

• dotn take longer than 10 days

• do not over medicate

Pt teaching

• s/s of bleeding

Evaluation

• revists pt pain before and after med goven

​Nonsteroidal Anti-inflammatory Drugs (NSAIDS)

Meds:

• Aspirin ​

  Ibuprofen (Advil or Motrin)​

  Naproxen (Aleve)​

  Indomethacin ​

  Ketorolac (Toradol) ​

MOA:

• inflamatory suppression, pain relief, fever reduction

Complications:

• GI discomfort

• impred kindey funtion

• Salicylism/Aspirin toxicity (aspirin only)​

• Reye’s Syndrome (aspirin only, rare)​ —> don’t give to sick kids

Contraindications:

Interactions:

Nursing Implications:

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Meds:

MOA:

Complications:

Contraindications:

Interactions:

Nursing Implications:

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