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best predictor of animal physiology
size
Genotype +_______ = phenotype
environment
What’s Cheaper, regulation or conformity?
Conformity
Unidirectional Flow
highly efficient lungs where “air” moves in one continuous direction, allowing for continuous gas exchange and higher oxygen uptake
Unidirectional Flow in Birds
using air sacs to move air through looped airways (parabronchi) in a single direction, maximizing oxygen extraction
Unidirectional flow in Lizards/Iguanas
lungs that have interconnected chambers (brachial tubes) for continuous airflow.
Unidirectional Flow in Fish
the one-way movement of water through their gills
Countercurrent Exchange
Maintains a constant gradient for heat or O₂ transfer, good for keeping extremities warm
Concurrent exchange typically allows how much transfer?
80/20
What alternative respiratory surfaces do some fish use
Gills, skin, buccal cavity, intestine, and swim bladder
What does a low P50 mean?
High oxygen affinity, better binding
What does high P50 mean?
Easier Oxygen unloading (low oxygen affinity)
What type of circulatory system do mammals have
Closed system with heart
Who has open circulatory systems
Insects (low pressure, high blood volume)
Arteries
Arteries carry blood away heart
Veins
veins carry blood to heart.
What adaptation helps animals at high altitudes
Lower P50 → higher O₂ affinity
What macromolecule has the most energy per gram?
Lipids
What increases metabolic rate?
Reproduction, digestion
What decreases metabolic rate
Hibernation, estivation (summer sleep)
What is the thermal neutral zone
Range where metabolic rate is minimal for thermoregulation. Lower than body temperature
How does body size affect metabolism
Smaller animals: higher mass-specific MR. Larger animals: higher overall MR.
Endotherm
Endotherms = mammals, birds.
Ectotherms
reptiles, amphibians, most fish.
Homeotherm definition
maintains constant internal temperature
Poikilotherm
an animal that cannot regulate its body temperature except by behavioral means such as basking or burrowing.
Poikilotherm example
Desert animals such as kangaroo rats
Why does water feel colder than air?
Conducts heat better than air.
What is a brain-cooling adaptation in dogs
Carotid rete (countercurrent heat exchange), they pant (advantage over rabbits)
Temperature specific sex determination
form of environmental sex determination in which the incubation temperature during a critical period of embryonic development, known as the thermosensitive period (TSP), determines the sex of the offspring (found in turtles, lizards, etc.)
What kidney adaptation helps desert animals retain water
Very long loops of Henle → highly concentrated urine.
Why are Antarctic fish considered “homeothermic”
Environment is constantly near freezing.
Osmoregulation
regulates everything, total solute concentration
Ionoregulation
Regulation of specific ions (e.g., Na⁺, Cl⁻, K⁺).
What muscle type supports long-distance migration?
Slow-twitch (red, high myoglobin)
What muscle type do sprinters use
Fast-twitch (white)
What type of feedback controls most hormone levels?
Negative feedback
What hormone signals nighttime
melatonin
What does progesterone do during pregnancy (think birth control)
Supports estrogen and maintains pregnancy
Thyroid hormone function?
Regulates metabolic rate and body temperature.
What cells support sperm development
Sertoli cells
What cells produce testosterone?
Leydig cells
Birds have how many ovaries?
One functional ovary (usually left).
Which animals have two hemipenes?
Snakes, lizards, sharks.
What species show temperature-dependent sex determination?
Many reptiles.
How do stronger stimuli affect neurons?
Increase frequency of action potentials.
Why are vertebrate neurons fast?
Myelination (insulation).
Where are graded potentials measured?
Dendrites and the cell body.
Cockroach nervous system type?
Polysynaptic
What animals have giant axons
Many invertebrates (e.g., squid).
What structures sense rotational balance in vertebrates
Semicircular canals.
Semicircular canals evolved from what?
lateral line
Sperm from what type of cells
Stroli
Testosterone from what type of cells
ladig
Why do Birds have one ovary
to reduce body weight for efficient flight
What is the lateral line system for?
Detecting water movement; analogous to vestibular system.
What provides more energy PER GRAM: sugars or fats?
fats (lipids)
Olfaction
airborne smell
Accessory olfaction
VNO = pheromones
What is the vomeronasal organ used for?
Detecting pheromonal cues.
What does a cup eye detect?
Light only; no image.
What is the limitation of a pinhole eye?
Dim image; needs lots of light.
Example of sensory arms race?
Bats' echolocation vs moths' anti-detection adaptations.
Do diving animals have specialized hemoglobin for oxygen storage?
No. Diving animals do not have special hemoglobin; they rely on myoglobin, lung volume, and blood volume instead.
How is circulation organized in birds
Birds have separate pulmonary and systemic circulatory systems, allowing efficient oxygen delivery.
Which animal shows a stronger Bohr shift: vole or capybara?
Vole — small mammals have a stronger Bohr shift to enhance oxygen unloading in active tissues.
Bohr Shift
shift in the oxygen dissociation curve caused by changes in the concentration of carbon dioxide or the pH of the environment.
What does a strong Bohr shift indicate?
Greater hemoglobin sensitivity to pH and CO₂, improving oxygen release during high metabolism.
How does the nervous system evolve over time?
Evolution adds new structures onto existing ones; older systems are not replaced.
What effect do organic phosphates (e.g., 2,3-BPG) have on hemoglobin?
They shift the oxygen dissociation curve right, decreasing oxygen affinity (↑ P50).
What does a rightward shift in P50 mean physiologically?
Hemoglobin releases oxygen more easily to tissues
Do camels undergo estivation?
No. Camels tolerate heat and dehydration but do not estivate.
How does whole-body metabolic rate relate to animal size?
Whole-body metabolic rate positively correlates with size — larger animals have higher total metabolism.
How does mass-specific metabolic rate relate to size?
Mass-specific metabolic rate is higher in smaller animals, despite lower total metabolism.