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What kind of interactions are occurring in cell differentiation?
cell-cell interactions
What is apoptosis?
cell death
What are the functions of neurotrophic factors?
They are needed to keep neurons alive, block apoptosis, and regulate expression
What is collateral sprouting?
Neighboring neuron would sprout its axon and take its place.
In human adolescence, which of the following is a white matter brain structure that will show an overall increase in neurogenesis?
hippocampus
When does neurogenesis in adulthood occur in women and men?
In women, neurogenesis occurs after menopause. In men, its with age.
Does the dendritic growth occur before birth or after birth?
After birth
What is epigenetics response?
Methylation of the gene for the cortical receptor
What is epigenetics?
study of factors that change gene expression without changing the gene sequences
What is the result of methylation?
less gene expression, high anxiety, low grooming, high stress
What are the 8 basic emotions suggested by Ekman?
anger, fear, sadness, disgust, contempt, surprise and happiness
What is the James-Lange Theory?
autonomic reaction triggers feeling — stimulus triggers perception/interpretation which triggers specific pattern of autonomic arousal (heart racing) which triggers a specific emotion (fear)
What was discovered in Schachter’s Experiment?
theory is truthful — autonomic makes you feel and cognitive systems let you know what emotions you are feeling
person in room with playful person felt joyful after
person in room with angry person felt angry after
Where does the high road pathway go?
passes through hippocampus — processed more
Where does the low road pathway go?
straight to the amygdala — less processing
What kind of feedback network is the HPA axis?
negative feedback network
What bodily function is NOT one of the symptoms of prolonged stress — increased cardiovascular tone, hypertension, digestive problems, depression, increased productivity
increased productivity
What are the heritability rules with Schizophrenia?
closer in relation, more likely to inherit
What is the hypofrontality hypothesis in schizophrenia?
frontal lobes are underactive in people with schizophrenia — decreased blood flow and reduced density of dendritic spines
What is the Dopamine Hypothesis?
Schizophrenia is caused by an excess of either dopamine release or dopamine receptors
What hypothesis studies PCP?
Glutamate Hypothesis
What is the primary receptor associated with the Glutamate Hypothesis?
NMDA receptor
What percentage of young adults have major depression?
19%
What percentage of depression cases coincide with suicidality?
13%
Which population reports the most of having mental illness? and what percentage?
college students, 32%
Is mental illness greater in men or women?
women
One in what postpartum women show symptoms of depression?
1 in 7
What are the brain changes associated with depression?
increased activation of prefrontal cortex and amygdala; decreased activity in hippocampus and anterior cingulate cortex
What are the monoamines?
Norepinephrine, dopamine, and serotonin
What is the function of Tricyclics—2nd gen antidepressant?
Inhibit reuptake of monoamines
What is the most effective treatment of depression?
CBT and SSRIs used together
What hormone is lowered in people with PTSD?
cortisol
What is the effect of anxiolytic drugs like Benzodiazepines on synapses?
Binding to GABAa receptors and enhancing GABA’s inhibitory actions
What kind of memory is delayed matching-to-sample task testing?
declarative memory
What is declarative memory?
clearly told
What is episodic memory?
whats happened throughout life
What is semantic memory?
facts
What is nondeclarative memory?
Muscle memory—things you know that you can show by doing
What memory is impaired by damage to the basal ganglia?
skill learning and procedural memory
What is priming?
A change in stimulus processing due to prior exposure to the stimulus
What type of memory is priming?
Nondeclarative
What is an example of operant conditioning?
Getting rewarded with candy each time you are quiet in Mass
What cells are actively encoding where the animal is in a certain area?
place cells
Where are place cells in the brain?
Hippocampus
What cells are in charge of the latitude and longitude matrix?
grid cells
Where are grid cells in the brain?
Medial entorhinal cortex
Where are boundary cells in the brain?
medial entorhinal cortex
Where are head direction cells located?
presubiculum
What is positive reinforcement?
get rewarded to increase behavior
What is negative reinforcement?
Remove an unpleasant stimulus to increase behavior
What is positive punishment?
Apply an unpleasant stimulus to decrease behavior
What is negative punishment?
Remove a pleasant stimulus to decrease behavior
What is the process of long-term memory?
Encoding, consolidation, and retrieval
What would happen if encoding is prevented?
Consolidation and retrieval would not occur
What does it mean for a memory to be consolidated?
brought into long-term storage
What does it mean for a memory to be retrieved?
Memory is brought out of consolidation to be used
What is the neurotransmitter associated with AMPA receptors?
Glutamate
Which hypothesis states that facial expression will effect emotion felt?
Facial feedback hypothesis
What brain regions showed decrease in love?
Posterior cingulate and amygdala
What is a common movement disorder related to classical neuroleptics?
Tardive dyskinesia
What is wrong with Patient K.C.?
brain damage from a motorcycle accident – frontal and parietal cortex
Is this episodic, semantic, skill learning, or priming: first day of school
episodic
s this episodic, semantic, skill learning, or priming: your knowledge of what a car is and how an engine works
semantic
Is this episodic, semantic, skill learning, or priming: mastering complex musical pieces
skill learning
Is this episodic, semantic, skill learning, or priming: if you show a person the word doctor he will be faster to recognise the word nurse than showing a different word
priming