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effects of crack last
5 minutes
As a drug circulates through the body
they are metabolized by the liver and eventually excreted by the kidneys in urine and/or via gastrointestinal tract in feces. Small amounts may also be eliminated in other ways, including in sweat, breast milk, and via the lungs
it is risky for women to use any drugs at all during pregnancy
including alcohol, and common over-the-counter products like cough medicine
Xylazine
large animal tranquilizer
natural opioid-like hormones released by the brain that can inhibit pain and induce
euphoria
chemical substance that helps relay nerve impulses in the brain is called a
neurotransmitter
a condition in which a stimulus evokes not only the sensation appropriate to it but also another sensation of a different character?
synesthesia
intoxication
The state of being mentally affected by a chemical (literally, a state of being poisoned).
substance misuse or abuse
The use of any substance in a manner inconsistent with legal or medical guidelines; may be associated with adverse social, psychological, or medical consequences; the use may be intermittent and with or without tolerance and physical dependence.
substance use disorder
A cluster of symptoms involving cognitive, bodily, and social impairment related to the continued use of a substance; a single disorder measured on a continuum from mild to severe.
11 DSM-5-TR criteria for substance abuse disorder. 2-3 for mild disorder, 4-5 for moderate disorder, 6 or more are evidence for severe disorder
Impaired control:
1. taking the substance in large amounts or over a longer period than originally intended
2. expressing a persistent desire to cut down on or regulate substance use, but being able to do so
3. spending a great deal of time getting the substance, using the substance, or recovering from its effects
4. Cravings
Social Problems:
5. Failing to fulfill major obligations at work, school, or home
6. Continuing to use substances despite being proven they make social situations work
7. Using substances at the expense of social, school, work, or recreational activities
Risky use:
8. Using the substances in which situations are dangerous to do
9. Continuing to use substances despite knowledge of problems
10. Developing tolerance to substances
11. Withdrawal symptoms
Behavioral Addiction
A form of addiction involving a compulsion to engage in an activity such as gambling, sex, or shopping, rather than a compulsion to use a substance.
One half of people with mental disorders also have
substance abuse disorders
risks associated with drug misuse
intoxication, unexpected side effects, unknown drug constituents, infection and injection drug use, legal consequences
neurotransmitter
A brain chemical that transmits nerve impulses.
effects of lsd last
12 or more hours
placebo effect
A response to an inert or innocuous substance given in place of an active drug.
social factors of drugs
the setting of when the dose takes place
the opioid epidemic takes
130 lives per year
depressant or tranquilizer, sedative-hypnotic
A drug that decreases nervous or muscular activity, causing drowsiness or sleep.
barbiturates
CNS depressants used to treat seizures, headaches, and sometimes used in euthanasia.
CNS depressants effects
-mood change
-slurr speech
-drowsiness
-mental function
anesthetic
A drug that produces a loss of sensation with or without a loss of consciousness.
tolerance for cns happens
sometimes for up to 15x the normal dose can develop repeated use
cocaine
a powerful and addictive stimulant, derived from the coca plant, producing temporarily increased alertness and euphoria
psychosis
A severe mental disorder characterized by a distortion of reality; symptoms might include delusions or hallucinations.
long-term effects of marijuana
respiratory problems, memory, mental health decline
hallucinogen
Any of several drugs that alter perception, feelings, or thoughts; examples are LSD, mescaline, and PCP.
LSD
a powerful hallucinogenic drug; also known as acid (lysergic acid diethylamide)
phencyclidine
PCP; drug originally developed as a surgical anesthetic that was discontinued due to adverse patients reactions; abusers of the drug often experience severe psychiatric manifestations
ketamine
a dissociative anesthetic drug, similar to PCP, that acts as an NMDA receptor antagonist
magic mushrooms
fungus that contains the psychedelic compounds psilocybin and psilocin. been used for thousands of years as a hallucinogen
inhalants
Substances whose fumes are sniffed or inhaled to give effect
people who use drugs are more likely to
commit violent crimes
treating a drug addiction like a mental illness is
cheaper than incarceration
Harm reduction strategies
-Needle-exchange programs
-Safe injection facility
-Provision of easy-to-use form of naloxone
-Free testing of street drugs
preventing drug misuse
Understand the context of drug use
Accurate education and information
Address underlying issues that we are escaping from
Poverty, oppression, violence
Depression, anxiety, isolation
The drugs most often associated with addiction and impairment are
psychoactive drugs
what factors can contribute to the way in which a person responds to a drug
genetic factors
weight
pregnancy
main factors in the initial use of drugs
availability
peer influence
refers to the subjectively pleasing effects of a drug, usually felt soon after the drug is taken
high
Which infections and diseases are associated with the use of unsterile needles and syringes by people who misuse drugs?
HIV
hepatitis C
An opioid is
any of several natural or synthetic drugs that relieve pain and cause drowsiness or euphoria
GHB is a CNS depressant that in large doses or when taken in combination with alcohol or other depressants can cause
loss of consciousness
death
Central nervous system depressants were mainly developed as
antianxiety agents
effects of CNS stimulants
greater muscular tension
increased blood pressure
accelerated heart rate
Cocaine is usually derived from the leaves of the
cocoa shrubs that grow in the Andes Mountains.
CNS depressants known for their calming properties are given in combination with
anesthetics before operations and other medical or dental procedures.
amphetamines
They are stimulants.
They affect the central nervous system.
They are also known as uppers.
The activity of the nervous or muscular system is speed up by central nervous system:
stimulants
38 states and the District of Columbia (DC) have legalized medical marijuana, and
24 states and DC allow for recreational usage.
most common CNS stimulants
nicotine
ephedrine
cocaine
In small doses, amphetamines
change sleep patterns
make people feel more alert
a potent central nervous system stimulant
amphetamine
A drug that increases nervous or muscular activity is called a
stimulant
widely abused prescription drugs
medication to treat pain
medication to treat ADHD
medication to treat anxiety
With more than 50 million current users, the most widely used federally illegal drug in the United States is:
cannabis
part of the definition of prescription drug abuse according to the National Institute on Drug Abuse
the use of a medication just for the experience
the use of a medication without a prescription
the use of a medication in a way other than prescribed
What is the best solution for drug abuse?
prevention
names of synthetic recreational drugs marketed as stimulants with properties like those of cocaine or amphetamine
White Rush
Bath salts
reasons that people in the United States have for wanting to keep illegal drugs illegal
Drugs would be more socially acceptable if they were legalized.
Legalizing drugs might expose more people to abuse and dependence.
Allowing easier access to drugs might increase drug use among children and teenagers.
What is the purpose of a harm reduction strategy in drug treatment?
to minimize the negative effects of drug use and abuse
psychoactive drug
A drug that can alter a person's consciousness or experience.
addiction
A chronic disease that disrupts the brain's system of motivation and reward, characterized by a compulsive desire and increasing need for a substance or behavior, and by harm to the individual and/or society.
addictive behavior
Compulsive behavior that is both rewarding and reinforcing and is often pursued to the marginalization or exclusion of other activities and responsibilities.
tolerance
Lower sensitivity to a drug or substance so that a given dose no longer exerts the usual effect and larger doses are needed.
withdrawal
Physical and psychological symptoms that follow the interrupted use of a drug that a person has become dependent on; symptoms may be mild or life threatening.
Development of Substance Abuse Disorder
when something brings pleasure, a person gets used to it, then repeated use becomes necessary to avoid withdrawal
Gambling Disorder
affects 1-2.5% of American adults. 75% of students have reported engaging in the common behavior and 6% have a serious addiction that results in unmanageable debts, psychological difficulties, and failing grades. 16x more likely to commit suicide
Since the pandemic, the sharpest rise in deaths via drug use have been
among people ages 25-54, Black men, and Native Americans/Alaskan Natives
Factors associated with trying drugs
Male (twice as likely as females)
Troubled childhood
Thrill-seeking
Dysfunctional family background
Peer group that accepts drug use
Trouble at school
Being poor
Girl dating an older boy
Risky sexual behavior
Factors associated with not using drugs
•Perceiving drug use as risky, and disapproving of it
•Positive self-esteem and self-concept
•Assertive, independent thinkers not controlled by peer pressure
•Self-control
•Social competence
•Optimism
•Academic achievement
•Religiosity
•Open communication with parents
in states with legal syringe service programs, where used syringes can be traded for new ones
HIV and HVC rates have dropped by about 50%
Drug arrests account for
the second highest counts of all crimes
Cocaine and amphetamines
increase the amount of dopamine
6 groups of psychoactive drugs
1. Opioids
2. Central nervous system (CNS) depressants
3. Central nervous system stimulants
4. Marijuana
5. Hallucinogens
6. Inhalants
opioid
Any of several natural or synthetic drugs that relieve pain and cause drowsiness and/or euphoria; examples are opium, morphine, and heroin; also called a narcotic.
sedation
The induction of a calm, relaxed, often sleepy state.
benzodiazepines
CNS depressants used for sleep and anxiety disorders.
central nervous system depressants
alcohol, benzodiazpines and opioids (heroin, meperidine, morphine, oxycodone, vicodin)
Rohypnol
(flunitrazepam) A sedative that is 10 times more potent than Valium; used as a "date rape drug." Has never been approved for use by the FDA
club drug
a drug made to closely resemble a common illegal drug in chemical structure and effect
a potentially lethal dose of fetanyl is smaller than
a dime
GHB
(gamma hydroxybutyrate) A central nervous system depressant that can be produced in clear liquid, white powder, tablet, and capsule form.
Almost 70% of Americans who died from an overdose between 2000-2021
had no college experience
stimulants
A drug that increases nervous or muscular activity.
a woman who uses cocaine during pregnancy has a higher rate of
miscarriages, stillbirth, premature labor
Amphetamines
drugs that stimulate neural activity, causing speeded-up body functions and associated energy and mood changes
depersonalization
A state in which a person loses their sense of reality or perceives their body as unreal.
marijuana
A plant whose leaves, buds, and flowers are usually smoked for their intoxicating effects
altered states of consciousness
Profound changes in mood, thinking, and perception.
synesthesia
A condition in which a stimulus evokes not only the sensation appropriate to it but also another sensation of a different character, such as when a color evokes a specific smell.
flashback
A perceptual distortion or bizarre thought that recurs after the chemical effects of a drug have worn off.
MDMA
A compound drug related to both amphetamines and hallucinogens, especially mescaline; commonly called "ecstasy." Can affect concentration, judgement, and driving ability. Can cause paranoia, dangerously high body temperature, kidney failure, dehydration
bath salts
mephedrone or a related stimulant packaged as bath salts but intended for use as a psychoactive drug
65% of all state and federal prisoners
meet the diagnosis for substance abuse disorder
the cost of drug overdose fatalities is
$1 trillion per year
methadone
A treatment that activates opiate receptors slowly than other opiates, dampening the high that addicts get. Eases withdrawal.
Naltrexone
opioid antagonist
drug treatment centers
outpatient drug-free treatment, short term treatment, maintenance therapy, therapeutic communities