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neural transmission, neurotransmitters, & hormones
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neural transmission
occurs when a neuron is activated, or fired - sends out an electrical impulse (transfer of information between neurons)
action potential
the change in electrical potential that propagates along the axon of a neuron during the transmission of a nerve impulse or the contraction of a muscle
all-or-nothing principle
a neurons reaction of either firing with a full strength response or not firing
depolarization
when there's a sight in a neuron's electrical charge that allows an action potential to occur
refractory period
in neural processing, a brief resting pause that occurs after a neuron has fired; subsequent action potentials cannot occur until the axon returns to its resting state
resting potential
the condition of the neuron when its resting - the value its membrane potential keeps as long as its not receiving stimulation or undergoing an action potential
reuptake
a neurotransmitters’ re-absorption by the sending neuron
threshold
the level of stimulation required to trigger a neural response
multiple sclerosis
a chronic inflammatory disease of the central nervous system, causing motor & sensory impairment by progressive demyelinization (deterioration of myelin sheaths)
myasthenia gravis
a chronic autoimmune disorder in which antibodies destroy the communication between nerve cells & muscles, resulting in weakness
excitatory neurotransmitters
describes a neurotransmitter that causes a postsynaptic neuron to propagate more action potentials
inhibitory neurotransmitter
describes a neurotransmitter that causes a postsynaptic neuron to propagate fewer action potential
dopamine
a neurotransmitter that:
→ helps the brain coordinate & initiate physical movement
→ is released in response to pleasurable experiences (makes you feel good & more likely to do that thing again)
→influences motivation & goal-directed behavior
→influences cognition & executive function
oversupply: schizophrenia, euphoria, psychosis
undersupply: parkingson's disease, adhd
serotonin
a neurotransmitter that regulates mood, sleep, arousal, appetite, & digestion
oversupply: serotonin syndrome
undersupply: linked with depression, anxiety, worry, nervousness, sleep difficulties, etc.
norepinephrine
a neurotransmitter that:
→is involved in prompting wakefulness, alertness, & arousal
→is released in response to stress & helps initiate the fight or flight response
oversupply: stress, anxiety, associated with manic episodes in bipolar disorder
undersupply: depressed mood, sleep problems
glutamate
a major excitatory neurotransmitter that makes it more likely for a neuron to fire & increases brain activity, also involved in learning & memory
oversupply: seizures, migraines
undersupply: cognitive impairments, learning deficits
GABA
a major inhibitory neurotransmitter that makes it less likely for a neuron to fire & reduces brain activity
oversupply: drowsiness, muscle weakness, cognitive impairment due to reduced brain activity
undersupply: anxiety, insomnia, chronic pain, depressed mood, seizures
endorphins
a neurotransmitter that:
→regulates the perception of pain, acting as the brain's natural opiates
→enhances mood, feelings of euphoria & pleasure
→can reduce the body's stress response
oversupply: n/a
undersupply: increased sensitivity to pain
substance p
a neurotransmitter that:
→is involved in the perception of pain, helps transmit pain signals from the body's skin, muscle, & tissues to the central nervous system
→plays a role in promoting inflammation in response to injury
→involved in regulating emotion & social behavior
oversupply: n/a
undersupply: n/a
acetylcholine
a neurotransmitter that:
→enables movement, transmitted from motor neurons to muscles
→is involved in learning & memory, many ACh receptors are in the hippocampus
oversupply: blurred vision, nausea & vomiting, slow heart rate, difficulty breathing, paralysis due to wearing out ACh receptors
undersupply: myasthenia hravis, alzeimer's disease
hormones
chemical messengers that are manufactured by the endocrine glands, travel through the bloodstream, & affect other tissues
adrenaline
a hormone that activates the sympathetic nervous system, like fight or flight
leptin
a hormone that helps manage energy, signals the hypothalamus the body has enough fat stored to function normally (tells you when you're full)
ghrelin
a hormone your stomach produces & releases, it signals your brain when your stomach is empty & it's time to eat (tells you when you're hungry)
melatonin
a hormone known to regulate sleep & wake cycles, its released by the pineal gland into the bloodstream when sleep is prompted
oxytocin
a hormone found in mammals that's associated with boding, empathy, & trust, produced by the hypothalamus & increased by the pituitary gland
pituitary gland
the endocrine system's most influential gland - under the influence of the hypothalamus, regulates growth & controls other endocrine glands