ch 36 adrenal steroids

what are the layers of the adrenal cortex

glomerulosa, fasciculate, reticularis

what do the layer of the adrenal cortex do

release hormones

what are hormones

steroids or corticosteroids

what do glucocorticoids do

use glucose to meet body needs

what diseases are associated with glucocorticoid deficiency

cushing and addison

what is another name for aldosterone

mineralocorticoid

what does aldosterone do

regulate BP by regulating electrolytes

what are examples of glucocorticoids

cortisol and cortisone

what do cortisol and cortisone do

gluconeogenesis, lipolysis, inhibit glucose reuptake

what is the HPA axis of glucocorticoids

H releases CRH, A.Pit ACTH adrenal cortisol

when are glucocorticoid levels highest

when waking up

how is glucocorticoids regulated

as levels rise less releasing factos are released

how does stress impact glucocorticoids

increases cortisol

what is catabolism

metabolism of carbs, protein and fates

what is gluconeogenesis

making glucose in liver

what is protein catabolism

breakdown of proteins

what are clinical indications of glucocorticoids

replacement therapy, inflammation hypercalcemia from cancer

what are adverse effects of glucocortcoids

increased appetite weight loss hirsutism

what are mineralocorticoids

secreted by glomerulosa to regulate fluid balance

what condition causes mineralocorticoid deficiency

removal of adrenal gland

How does mineralocorticoid aldosterone regulate fluids

increases reabsorption of Na ions

how do steroids affect metabolism

increased BP and hypertension, electrolyte balance and cardiac function

what are contraindications for steoids

GI ilceration, renal disease, diabetes

what are eye issues that arise from steroids

cataracts and glaycoma