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Disulfiram use
Used to prevent acetaldehyde turning into acetate, causing you to feel sick faster when drinking
Fomepizole use
Used to stop methanol from turning into formaldehyde (toxic), causing methanol to be excreted it as is
Methanol symptoms
Ocular toxicity, blindness, acidosis, brain damage, increased anion gap
Erythrocyte transketolase is measured to
Determine thiamine levels
Ethylene glycol (antifreeze) mechanism and symptoms
Creates glyoxylic acid and oxalic acid, both toxic to the body and leads to lactic acidosis, increased anion gap, renal failure, crystals in urine
Ethanol metabolism creates too much
NADH
Ethanol and tylenol (acetaminophen) create
A toxic substance (NAPQI) which uses up glutathione and thus can't reduce reactive oxygen species
To treat, give NAC (N acetyl cysteine)
Asian Flush cause
Deficiency of acetaldehyde DH which helps indicate when to stop drinking
