Sodium Bicarbonate in Pharmacology

These flashcards cover key concepts related to Sodium Bicarbonate, including its classification, mechanism of action, indications, contraindications, dosing guidelines, and potential side effects.

Sodium Bicarbonate

An alkalinizing agent and electrolyte used in various medical conditions.

Mechanism of Action

Reacts with H+ ions to form water and CO2.

Indications for Sodium Bicarbonate

Wide complex tachycardia or arrest from TCA overdose, acidosis, cardiac arrest due to suspected pre-existing hyperkalemia or ASA overdose.

Contraindications for Sodium Bicarbonate

Alkalosis, severe pulmonary edema, abdominal pain of unknown origin, hypocalcemia, hypernatremia.

Adult Dose of Sodium Bicarbonate

1 mEq/kg slow IV, IO; repeat 0.5 mEq/kg every 10 minutes as needed.

Pediatric Dose of Sodium Bicarbonate

Same as adult dose.

Potential Side Effects of Sodium Bicarbonate

Metabolic alkalosis, hypoxia, increased intracellular PCO2, increased tissue acidosis, electrolyte imbalance, seizures.

Indication of Metabolic Alkalosis

Condition that can occur as a side effect of sodium bicarbonate administration.

Effect of Sodium Bicarbonate on Electrolytes

Can lead to electrolyte imbalance.