Handling of Cytotoxic Agents- Dr.K

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32 Terms

1
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USP chapter _____ sets standards for handling hazardous drugs in healthcare settings.

800

2
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What organization maintains a list of HDs (hazardous drugs) used in healthcare?

NIOSH

3
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What organization provides standards for workplace safety?

OSHA

4
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What organization sets regulations for hazardous waste management?

EPA

5
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To be considered a hazardous drug it must exhibit _____ or more of the following:

  • carcinogenicity

  • teratogenicity

  • developmental toxicity

  • organ toxicity

  • genotoxicity

one

6
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Term that describes things that may cause mutations leading to cancer/tumors:

carcinogenicity

7
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Term that describes things known to cause fetal abnormalities:

teratogenicity

8
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What term is used to describe things that interfere with normal growth, differentiation, development, or behavior?

developmental toxicity

9
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Genotoxicity damages _______.

DNA

10
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NIOSH also classifies HDs into groups. What are the 3 groups?

  1. antineoplastic drugs

  2. non-antineoplastic drugs

  3. drugs that pose a reproductive risk

11
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Exposure to hazardous drugs occurs through _______________, __________________, ______________________, and ___________________.

  • inhalation

  • absorption

  • injection

  • ingestion

12
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What are some examples of opportunities where you might be exposed to hazardous drugs?

  • dispensing

  • compounding

  • administration

13
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To minimize exposure to HDs, facility controls are ____________ areas ______________ from non HD for receipt/unpacking, storage, and compounding.

facility controls are designated areas separated from non HD for receipt/unpacking, storage, and compounding.

14
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To minimize exposure to HDs, compounding MUST occur within a __________ located in a _____________.

compounding MUST occur within a C-PEC located in a C-SEC.

15
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What are some examples of C-PEC? (list 2)

  1. biological safety cabinet

  2. compounding aseptic containment isolator (CACI)

16
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Should C-PEC and C-SEC be externally or internally vented?

  • know

externally

17
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Should C-PEC and C-SEC be negative or positive pressure?

  • know

negative

18
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All areas where HDs are handled and all reusable equipment must be ______________, __________________, and ________________.

must be deactivated, decontaminated, and cleaned.

19
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If sterile compounding reusable equipment must also be ________________.

disinfected

20
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How many gloves should you put on when handling HDs?

  • KNOW

2 - DOUBLE GLOVEEEEEEE

21
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When handling HDs, gowns must be ____________ and resist_________________________.

gowns must be disposable and resist permeability by HDs.

22
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What type of respirator is commonly used when handling HDs?

  • know

N95 (NIOSH certified)

23
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Is a surgical mask okay to wear when handling HDs?

NOPE

24
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What situations would you not wear an N95 and wear a full-facepiece chemical cartridge respirator? (3 situations)

  1. large spills

  2. deactivating, decontaminating, cleaning under PEC

  3. known airborne exposure

25
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WHAT IS the most urgent action if accidental exposure occurs?

get the drug/chemical OFF OF THE PERSON

26
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Who must be trained in spill control?

all personal who may be required to clean up a HD spill.

27
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Where should spill kits be located?

all areas where HDs are commonly handled

28
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When should spill kits be cleaned?

IMMEDIATELY

29
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What should HDs be labeled when disposing?

“cytotoxic waste only”

30
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What goes in BLACK bulk chemo bins?

  • partially empty bags, vials, syringes

31
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What goes in YELLOW trace chemo bins?

  • gloves, gowns, shoe covers

  • empty IV bags, syringes, vials

32
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Main difference between things put in yellow and black chemo bins?

in yellow empty syringes, vials, bags etc. , in black only PARTIALLY empty things