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Hydrogen Peroxide
Potassium Permanganate
Benzoyl Peroxide
OXIDIZING AGENTS
Hydrogen Peroxide
OXIDIZING AGENTS
MOA: liberation of nascent oxygen in living tissues
Potassium Permanganate
OXIDIZING AGENTS
MOA: protein denaturation
Nascent
Liberates one Oxygen.
Free Radical causes tissue damage to the microbe.
Benzoyl Peroxide
OXIDIZING AGENTS
- White granular powder that is explosive in its pure form
- Formulated with 30% water to make it safer to handle
- Induces proliferation of epithelial cells; both keratolytic and keratogenic
Chlorine
Iodine
Povidone- Iodine
Halogen-Containing Compounds
Chlorine
Halogen-Containing Compounds
- Used in the disinfection of water supplies
- MOA: formation of hypochlorous acid when dissolved in water
Iodine
Halogen-Containing Compounds
- One of the most effective and useful germicides
- MOA: iodination of phenylalanyl and tyrosyl residues in and oxidation of sulfhydryl groups in proteins
Povidone- Iodine
Halogen-Containing Compounds
- Complex of iodine with the nonionic surfactant PVP (aka iodophor)
- Extremely water soluble and releases iodine very slowly
- Nontoxic, nonvolatile, and nonstaining form of iodine that is not irritating to the skin or to wounds
- Used as an aqueous solution for presurgical disinfection of the incision site, to treat infected wounds and damage to the skin, and against local bacterial and fungal infections.