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Rheumatic Fever (RF)
Inflammatory disease occurs after Group A Beta-haemolytic streptococcal throat infection
Rheumatic Fever (RF)
Self-limiting
Rheumatic Fever (RF)
Risk factors: 5-15 Female, Housing and socioeconomic
status, Rainy season, Genetic predisposition
Rheumatic Fever (RF)
Acute febrile-like illness (2-3 weeks after streptococcal throat infection)
Joints
(swelling and pain of larger joints like knee, ankle,
elbow and wrist occurring in rapid succession - "migratory
arthritis")
Heart
(causes inflammation of the whole layers of the heart -
PANCARDITIS) - Palpitation, chest pain, shortness of breathe,
leg swelling, etc.
Skin & subcutaneous tissues
(non-itching macular rash and painless mobile nodules over joints and spines)
Central Nervous System
(a late manifestation) - abnormal movements of the limbs with muscle weakness and emotional labiality.
Modified Jones Criteria
2 major or 1 major + 2 minor manifestations + strep infection
Major
Carditis, Polyarthritis, Erythma marginatum - rash, Subcutaneous nodules, and St. Vitus Dance
St. Vitus Dance
The Fifth Manifestation (Sydenham's Chorea)
St. Vitus Dance
also known as chorea and reflects CNS involvement
Chorea
refers to sudden, aimless movements of extremities, involuntary facial grimaces, speech disturbances, emotional lability and muscle weakness
Minor
Arthralgia, Fever, elevated esr and crp and prolonged pr interval in ecg.
Salicylates (ASA)
control inflammatory process esp. joints, dec fever and discomfort
Rheumatic Heart Disease (RHD)
Most common complication of RF
Permanent
There is no cure for rheumatic heart disease and the damage to the heart valves are?
Rheumatic Heart Disease (RHD)
Damage to valves leading to stenosis or regurgitation with resultant hemodynamic disturbance.
Kawasaki disease
causes swelling (inflammation) in children in the walls of small to medium-sized blood vessels that carry blood throughout the body.
Kawasaki disease
Self limiting but 20% children without treatment develop cardiac disease
C
Conjunctivitis (pink eye)
R
rash
A
Arthritis
S
Strawberry tongue
H
Hands (peeling skin)
Irritability
hallmark of Kawasaki Disease
Myocardial Infarction
is the principal cause of death in patients with Kawasaki disease.
Conjunctival injection
is a common condition that refers to the inflammation and dilation of blood vessels of the eye that supply the conjunctiva.
Kawasaki disease
treatment: high-dose IVIG along with salicylate therapy.
high-dose IVIG
has been shown to reduce the duration of fever and the incidence of coronary artery abnormalities when given within the first 10 days of illness and optimally within the first 7 days
Aspirin
is given initially in an anti-inflammatory dosage to control fever and symptoms of inflammation.
Cardiac tamponade
Compression of heart by blood and other effusion
(clots) in pericardial sac → restricts normal heart
movement
Pericardiocentesis
is a procedure performed to remove pericardial fluid from the pericardial sac.
Ejection fraction (EF)
Is a measurement, expressed as a percentage, of how much blood the left ventricle pumps out with each contraction. Normal EF is >50% to 70%.
2D Echo
Enables visualization and measurements of turbulence,
accentuation, direction, and decreases/ increases in blood
flow, along with pressure gradients
2D Echo
Uses high-frequency sound waves obtained by a transducer to produce an image of cardiac structure
Angiography
Assess route of blood flow in heart & major blood vessels
ABG
Helpful in differentiating between cardiac and pulmonary
pathologies
ABG
arterial blood gas
ABG
Important when the child is at risk or complications such as
acidosis and shock
Cardiac catheterization
is a procedure used to show on a computer monitor diseases that affect the heart, the cardiac valves or the coronary arteries.
Cardiac catheter
is a thin, flexible plastic tube that is moved through a blood vessel until it reaches the heart. X-ray monitoring is used to guide the catheter.
Left heart catheterization (arterial catheter)
This catheter is advanced through an artery in your groin region, elbow or wrist and into the heart's left ventricle.
Right heart catheterization (venous or flow-directed catheter)
The catheter is inserted through a vein in the groin region or at the elbow and then advanced to the right ventricle and the pulmonary artery.
Angiography
is a procedure that allows doctors to look at blood vessels in great detail using X-rays.
Angioplasty
If the doctors identify a narrowed portion (stenosis) of a blood vessel during the angiography procedure, they may stretch or widen it straightaway using a procedure called?
Angioplasty
means using a balloon to stretch open a narrowed or blocked artery.
Stent
most modern angioplasty procedures also involve inserting a short wire mesh tube, called a?
Stent
is left in place permanently to allow blood to flow more freely.
Open-heart surgery
is any type of surgery where the chest is cut open and surgery is performed on the muscles, valves, or arteries of the heart.
Cardiopulmonary bypass (CPB)
provides a bloodless field for cardiac surgery.
Cardiopulmonary bypass (CPB)
It incorporates an extracorporeal circuit to provide physiological support in which venous blood is drained to a reservoir, oxygenated and sent back to the body using a pump.