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Autograft: Source and coverage
Patient’s own unburned skin
May be meshed to cover larger areas or placed as a sheet on faces and hands for a smoother, more cosmetic appearance
Permanent
Autograft: Benefits and drawbacks
This is the ideal coverage for all patients’ burns and has the highest chance of wound closure.
May be delicate if meshed widely before application. Staple removal may be tedious.
Cultured epithelial autograft (CEA): Source and coverage
Patient’s own skin sample is sent to a laboratory, where the epidermis is grown in larger patches.
Permanent
Cultured epithelial autograft (CEA): Benefits and drawbacks
Is a good choice in patients with large burns of 70% or more TBSA burn who do not have enough unburned skin to use as donor for autografting
Is extremely expensive, very fragile, and susceptible to infection once applied. Dermal layer will never regenerate.
Integra(Artificial skin): Source and coverage
Two-layer man-made silicone membrane used to replace dermis and is covered with autograft
Permanent
Integra(Artificial skin): Benefits and drawbacks
May provide a functional dermis and better chance of wound closure
High risk for infection of the Integra and subsequent graft loss
Allograft: Source and coverage
Cadaver skin
Temporary
Allograft: benefits and drawbacks
Used as a temporary covering once eschar is removed to help close and protect wound
Will eventually reject and have to be replaced by permanent grafting
Xenograft: Source and coverage
Pig (most common) or bovine (cow) skin
Temporary
Xenograft: Benefits and drawbacks
Used as a temporary covering once eschar is removed to help close and protect wound
Will eventually reject and have to be replaced by permanent grafting
