Action Potentials and Nerve Physiology

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Vocabulary-style flashcards covering nerve physiology, muscle fiber types, electrical principles, and clinical electrotherapy parameters based on lecture notes.

Last updated 4:08 AM on 6/25/26
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33 Terms

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Action Potential

Rapid depolarization and repolarization of a nerve membrane.

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All-or-none Principle

A principle stating that an action potential occurs completely or not at all, with no partial potentials.

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Absolute Refractory Period

A period where no new action potential can occur because Na+Na^+ channels are inactivated.

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Relative Refractory Period

A period where an action potential can occur but requires a stronger stimulus because some Na+Na^+ channels have recovered.

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Saltatory Conduction

The process in myelinated nerves where an action potential "jumps" from one Node of Ranvier to another, making conduction faster and more energy efficient.

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Factors Increasing Conduction Velocity

Larger axon diameter, more myelination, and higher temperature.

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Orthodromic Propagation

The normal direction of transmission, defined as CNS to Muscle for motor nerves and Periphery to CNS for sensory nerves.

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Antidromic Propagation

Nerve transmission in the opposite of its normal direction (e.g., Distal to Proximal), commonly seen during electrical stimulation.

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Rate Coding

Increasing force by increasing the number of action potentials and frequency of firing.

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Henneman's Size Principle

The recruitment order in normal voluntary contraction where Type I fibers are recruited first, followed by Type IIa and then Type IIx.

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NMES Recruitment Pattern

The activation of large diameter axons and Type II fibers first, leading to greater muscle fatigue.

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Type I Muscle Fibers

Slow twitch, fatigue-resistant aerobic fibers used for endurance, characterized by smaller axons.

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Type II Muscle Fibers

Fast twitch, power-oriented anaerobic fibers that fatigue quickly and have larger axons.

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Power Formula

Power=Force×VelocityPower = Force \times Velocity

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Cathode

The negative electrode (-) which is electron-rich and produces depolarization and excitation.

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Anode

The positive electrode (++) which is electron-deficient and produces hyperpolarization.

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Voltage

Also called electrical potential, it represents electrical pressure measured in Volts (VV).

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Current

The flow of electrons measured in Amperes (AA), typically expressed in milliamperes (mAmA) or microamperes (μA\mu A).

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Charge Formula

Charge=Current×TimeCharge = Current \times Time; measured in Coulombs (CC).

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Impedance

The opposition to current flow, which can be increased by air pockets, dry skin, or cracked electrodes.

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Ohm's Law

V=I×RV = I \times R, where VV is Voltage, II is Current, and RR is Resistance.

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Direct Current (DC)

Also called Galvanic current; a continuous flow in one direction with long pulse durations, used for iontophoresis and wound healing.

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Alternating Current (AC)

A current that continuously changes direction, such as Russian stimulation or Interferential current.

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Phase

One portion of a pulse; waveforms can be monophasic, biphasic, or triphasic.

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Charge (Waveform Property)

Represented by the area under the curve; two different waveform shapes can have the same charge if their area is identical.

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Accommodation

When a nerve becomes less responsive to continuous stimulation; prevented by modulation, ramping, or burst patterns.

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Amplitude Depth Relationship

Higher intensity current activates deeper tissues, while lower intensity activates superficial tissues.

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Rheobase

The minimum current intensity needed to stimulate tissue using a very long pulse duration.

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Chronaxie

The pulse duration required to stimulate tissue using an intensity of 2×Rheobase2 \times Rheobase.

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Tetanic Contraction

A sustained contraction due to rapid stimuli, typically occurring at 5070pps50-70\,pps. (Pulses per second).

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Current Density

Formula: CurrentDensity=CurrentElectrodeAreaCurrent\,Density = \frac{Current}{Electrode\,Area}. Higher density results from smaller electrodes.

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Electrode Distance

Closer placement results in superficial current, while farther placement allows for deeper current penetration.

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Duty Cycle

The ratio of ON time to OFF time (e.g., 10sec10\,sec ON : 50sec50\,sec OFF); lower duty cycles result in less fatigue.