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Risk
Risk is the likelihood of harm arising from exposure to a hazard.
IEP
IEP is the pH at which a soluble protein has no net charge and will precipitate out of solution
Proteome
The proteome is the entire set of proteins expressed by a genome
ER
The endoplasmic reticulum (ER) forms a network of membrane tubules continuous with the nuclear membrane
Golgi apparatus
The Golgi apparatus is a series of flattened membrane discs
Lysosomes
Lysosomes are membrane-bound organelles containing a variety of hydrolases that digest proteins, lipids, nucleic acids and carbohydrates
Vesicles
Vesicles transport materials between membrane compartments
Channels
Channels are multi-subunit proteins with the subunits arranged to form water-filled pores that extend across the membrane.
Resting membrane potential
Resting membrane potential is a state where there is no net flow of ions across the membrane
Action potential
An action potential is a wave of electrical excitation along a neuron’s plasma membrane
Microtubules
Microtubules are hollow cylinders composed of the protein tubulin. They radiate from the microtubule organising centre (MTOC) or centrosome.
Point count
A point count involves the observer recording all individuals seen from a fixed point count location.
Taxonomy
Taxonomy involves the identification and naming of organisms and their classification into groups based on shared characteristics
Phylogenetics
Phylogenetics is the study of the evolutionary history and relationships among individuals or groups of organisms
bacterium
E. coli
plant
Arabidopsis thaliana
nematode
C. elegans
arthropod
Drosophila melanogaster
Latency
Latency is the time between the stimulus occurring and the response behaviour
frequency
Frequency is the number of times a behaviour occurs within the observation period.
duration
Duration is the length of time each behaviour occurs during the observation period
evolution
Evolution is the change over time in the proportion of individuals in a population differing in one or more inherited traits
selection pressures
Selection pressures are the environmental factors that influence which individuals in a population pass on their alleles.
HW principle
The Hardy-Weinberg (HW) principle states that, in the absence of evolutionary influences, allele and genotype frequencies in a population will remain constant over the generations
Absolute fitness
Absolute fitness is the ratio between the frequency of individuals of a particular genotype after selection, to those before selection
Relative fitness
Relative fitness is the ratio of the number of surviving offspring per individual of a particular genotype to the number of surviving offspring per individual of the most successful genotype
Coevolution
Co-evolution is the process by which two or more species evolve in response to selection pressures imposed by each other
Red Queen hypothesis
The Red Queen hypothesis states that, in a co-evolutionary relationship, change in the traits of one species can act as a selection pressure on the other species
Meiosis
Meiosis is the division of the nucleus that results in the formation of haploid gametes from a diploid gametocyte
Homologous chromosomes
Homologous chromosomes are chromosomes of the same size, same centromere position and with the same sequence of genes at the same loci.
Independent assortment
Each pair of homologous chromosomes is positioned independently of the other pairs, irrespective of their maternal and paternal origin.
Hermaphrodites
Hermaphrodites are species that have functioning male and female reproductive organs in each individual
Monogamy
the mating of a pair of animals to the exclusion of all others
polygamy
individuals of one sex have more than one mate.
polygyny
one male mates exclusively with a group of females.
polyandry
one female mates with a number of males in the same breeding season.
honest signals
Honest signals can indicate favourable alleles that increase the chances of survival of offspring (fitness) or a low parasite burden suggesting a healthy individual.
Ecological niche
An ecological niche is a multi-dimensional summary of tolerances and requirements of a species
Fundamental niche
A species has a fundamental niche that it occupies in the absence of any interspecific competition
realised niche
A realised niche is occupied in response to interspecific competition
definitive host
The definitive host is the organism on or in which the parasite reaches sexual maturity.
transmission
Transmission is the spread of a parasite to a host
virulence
Virulence is the harm caused to a host species by a parasite
epidemiology
Epidemiology is the study of the outbreak and spread of infectious disease
herd immunity threshold
The herd immunity threshold is the density of resistant hosts in the population required to prevent an epidemic
null hypothesis
The null hypothesis proposes that there will be no statistically significant effect as a result of the experiment treatment
peer review
Specialists with expertise in the relevant field assess the scientific quality of a submitted manuscript and make recommendations regarding its suitability for publication.
validity
variables controlled so that any measured effect is likely to be due to the independent variable.
reliability
consistent values in repeats and independent replicates
accuracy
data, or means of data sets, are close to the true value.
precision
measured values are close to each other.
multifactorial experiment
A multifactorial experiment involves a combination of more than one independent variable or combination of treatments.
placebo effect
Placebo effect is a measurable change in the dependent variable as a result of a patient’s expectations, rather than changes in the independent variable.
in vitro
In vitro refers to the technique of performing a given procedure in a controlled environment outside of a living organism
in vivo
In vivo refers to experimentation using a whole, living organism
representative sample
A representative sample should share the same mean and the same degree of variation about the mean as the population as a whole
random sampling
In random sampling, members of the population have an equal chance of being selected.
systematic sampling
In systematic sampling, members of a population are selected at regular intervals.
stratified sampling
In stratified sampling, the population is divided into categories that are then sampled proportionally
statistically significant result
A statistically significant result is one that is unlikely to be due to chance alone