Functional Groups + pKa

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Last updated 3:00 AM on 9/25/26
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27 Terms

1
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Sulfuric Acid, pKa < 0

2
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Toluenesulfonic Acid or Tosic Acid, pKa < 0

3
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Hydrogen Halides, pKa < 0

4
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Hydronium Ion, pKa < 0

5
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Protonated alcohol or Ether, pKa < 0

6
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Nitric acid, pKa < 0

7
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Pyridinium Ion, pKa = 5

8
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Carboxylic Acid, pKa = 4-5

9
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Ammonium Ion, pKa = 9-10

10
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Thiol, pKa = 10

11
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Amide, pKa = 15-17

12
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Water, pKa = 15.7

13
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Alcohol, pKa = 16-18

14
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Ketone, pKa = 20

15
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Ester, pKa = 25

16
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Alkyne, pKa = 25

17
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Amine, pKa = 38

18
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Benzylic Hydrogen, pKa = 41

19
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Allylic Hydrogen, pKa = 43

20
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Aromatic, pKa = 43

21
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Alkene, pKa = 44

22
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Alkane, pKa = 50

23
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Aldehyde, pKa = 50

24
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Ether, pKa = 50

25
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Epoxide, pKa = 50

26
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Nitro, pKa = 8-10

27
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Nitrile, pKa = 9 or 25 ?