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Function of bones
support against gravity, leverage for muscles, protection of organs, blood cell production, storage of calcium and fat
Bones
solid network of living cells and protein fibers that are surrounded by deposits of calcium salts
Matrix
(2/3 of bone mass): Hydroxyapatite, calcium carbonate, other
Protein fibers
(1/3 of bone mass): collagen is majority of organic matrix mass + others
Periosteum
tough, connective tissue covering (joins with tendons and ligaments)
Bone marrow
inside bone cavities
Bone marrow (hemopoietic tissue)
Produces blood cells, red, in nearly every bone as a child
Adults: skull, vertebrae, ribs, sternum, pelvic gridle, proximal heads of humerus and femur
Bone marrow (fatty connective tissue)
Yellow, most red marrow turns into fatty yellow marrow; no longer produces blood
Shapes
long bones, short bones, irregular bones, flat bones, sesamoid bones
axial skeleton
supports central axis of body and encases viscera (soft organs)
Includes 80 bones
Skull (29)
Vertebral column (26)
Rib cage (25)
The skull
divided into cranial bones(8), facial bones(14), other associated bones(7)
Cranial bones held together by
immorable joints called sutures, flexible in young children (becomes fixed as you age)
Foramina
tiny holes in bones that allow nerves, blood vessels, and other structures to pass through
Foramen magnum
(largest opening) where medulla oblongata projects out from skull, allows for blood vessels and nerves to enter/leave the cranium
Hyoid
associated with voice, fuses from 3 bones in early adulthood, function: provides anchor for muscles of tongue and neck
Vertebral column
vertebrates (irregular bones consisting of several parts)
Spinal chord
runs through the foramen
Humans have __ vertebrae when adult
26
Cervical
Neck, 7 (C1 - C7)
C1 is known as the
atlas vertebra (holds head, nod yes)
C2 is known as the
axis vertebrae (turn head, rotate no)
Thoracic
12, articulate with the ribs, T1 - T2
Lumbar
5, lower back/major weight-bearing, L1 - L5
Sacral
5, fused to form the sacrum
Coccygeal
4, fused to form the coccyx
Intervertebral discs
fibrocartilaginous rings that contain a jelly-like fluid
Major role: bear weight, absorb pressure, prevent bones from rubbing
Thoracic cage
protects the visceral organs
Sternum (protects lungs+heart) made up of these bones
manubrium, body, xiphoid process
Ribs
12 pairs, connected to posteriorly to the vertebrae
Rib pair 1-7 connect to
sternum
Rib pair 8-10 connect to
cartilage
Rib pair 11-12
floating ribs
Appendicular skeleton
suspended from the axial skeleton, includes bones of limbs, pelvis, shoulder
Pectoral girdle (shoulder) components
clavicles, scapulae
Humerus
head articulates with scapula, distal condyle articulates with forearm
Radius
lines up with thumb, head articulates with humerus, biceps brachii attaches here
Ulna
trochlear notch articulates with humerus
Olecranon forms point of elbow ←Connected to elbow
bones of wrist and hand
two rows of carpal bones (8 per hand), proximal phalanges articulate with metacarpals
phalanges
3 phalanges/finger, 2 phalanges/thumb
Pelvic girdle (hips) components
formed by two coxae (hip bones)
coxa fusion, pubic symphysis
coxa fusion of
ilium, ischium, pubis
pubic symphysis
limits movement, disapates pressure (allows you to jump, helps with child birth for women)
pelvis formed by
coxae, sacrum, coccyx
tibia (thick)
tibial tuberosity, patellar tendon attaches here
anterior crest, medial malleolus
Fibuala (little bone)
articulation of head with tibia, lateral malleolus
Bones of ankle and foot
seven tarsal bones
heel bone (calcaneus)
major load-bearing bone
Osteogenic cells
Stem cells found in endosteum, periosteum, and central canals
Multiply continuously to produce new
Osteoblasts
Cells that create new bone
When surrounded by a calcified matrix, matures into osteocyte
Osteocytes
Mature bone cells, maintain normal bone structure
Osteoclasts (found on bone surface)
Secrete acids & enzymes to break down bony matrix and release minerals
Very large, may contain 50+ nuclei
Compact bone
Dense/tightly packed & arranged in osteons (haversian system)
Outer layer of all bones
Spongy bone
Spaces filled with red bone marrow
Inside bones, reduces weight of bones
Flat bone: Spongy vs Compact
Sandwich-like construction: two layers of compact bone enclosing a middle layer of spongy bone
Surface covered with periosteum
Ossification
Replacing tissues with bone
Intramembranous
Bone grows in membranes
Baby’s soft spots turn into bone, formation of clavicle
Endochondral
Bone replaces cartilage
Remodeling
Osteoclast activity balanced by osteoblast activity
(exercise)