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- Know the 4 structures and zones of the neuron
Input zone - dendrites
Integration zone - a cell body (or soma)
Conduction zone - axon
Output zone - axon terminals
Input zone:
Dendrites
- Incoming signals enter the neuron
Integration zone:
Cell Body/Soma
- Takes in signals and makes a decision on whether or not an action potential will fire
Conduction zone:
Axon
- transmit electrical and chemical signals away from the neuron's cell body toward other neurons, muscles, or glands
Output zone:
Axon terminals
- Point in the neurone from which signals are sent out
- Know different types of glial cells and what their functions are
- Astrocytes
- Microglia
- Oligodendrocytes
- Schwann cells
Astrocytes
regulate blood flow and form new synapses
Microglia
small cells that remove debris from injured cells
Oligodendrocytes
form myelin sheath in the brain and spinal cord
Schwann cells
provide myelin to cells outside the brain and spinal cord
Know the 3 components of the synapse and the direction of flow of information across the synapse
- Presynaptic membrane
- Postsynaptic membrane
- Synaptic cleft
Presynaptic membrane
on the axon terminal of the presynaptic neuron
Postsynaptic membrane
on the dendrite or cell body of the postsynaptic neuron
Synaptic cleft
a gap that separates the membranes
Myelin is important because
it is the "insulation" for our cells and speeds the conduction of action potentials.
People with alzheimers suffer from
demyelination
Nodes of Ranvier
gaps between sections of myelin where the axon is exposed
an area where electrical signals that pass down the axon are regenerated
What are the divisions of the autonomic nervous system
- Sympathetic nervous system
- parasympathetic nervous system
- enteric nervous system
Sympathetic nervous system
Responsible for Fight or flight
- Sympathetic activation prepares the body for action.
Parasympathetic nervous system
Responsible Feeding and sex
- The PNS tends to calm things down in the body, for example, decreasing heart and respiratory rate, as well as aids in functions like digesting food. In the parasympathetic division-NE increases activity but uses acetylcholine (Ach) as main neurotransmitter, which slows body activity.
- Activation is often in opposition to sympathetic activity.
Enteric nervous system
Nerve signals to the gut
- Know the general specializations of the lobes of the brain
- frontal
- parietal
- occipital
- temporal
Frontal
- most anterior region
- decision making, impulse control, higher order cognitive abilities, language and movement
Parietal
- lies between the frontal and occipital lobes
- sensation and perception
Occipital
- posterior region, visual processing
- processes binocular vision, color vision, shapes, etc.
Temporal
- lateral region, auditory processing
- hearing, some aspects of language, memory and emotion
The basal ganglia is important in...
motor control
The basal ganglia include 4 nuclei which are...
- caudate nucleus
- the putamen
- globus pallidus
- substantia nigra
The caudate nucleus and putamen make up a structure called the _____
striatum
The caudate nucleus, the putamen, and the globus pallidus. help _______
decide whether motion will or will not occur.
The substantia nigra is a major souce of ______
of the neurotransmitter dopamine. Loss of these dopamine neurons leads to Parkinson's disease
The limbic system includes structures important:
learning and memory
The limbic system includes:
- Amygdala
- Hippocampus and Fornix
- Thalamus
- Hypothalamus
- Cingulate gyrus
- olfactory bulb
Amygdala:
- emotional regulation and perception of odor
- Important for processing fear as well as pheromone cues
Hippocampus:
- learning
- memory
Fornix:
- learning
- processing emotions
Cingulate gyrus:
attention
Olfactory Bulb:
- sense of smell
- In species that rely heavily on their sense of smell, this structure is very large compared to the rest of the brain. In humans, it's pretty small because we don't use smell as much.
Thalamus:
- a cluster of nuclei that relays sensory information
- All sensory information coming into the brain, with the exception of smell, is processed by the thalamus before going on to other areas of the brain, including the cortex.
Hypothalamus:
- contains nuclei with many functions - also controls the pituitary
- Regulates LOTS of functions, including hunger, thirst, temperature, parenting behavior, and reproduction.
What are the 3 meninges:
- Dura mater
- Pia mater
- Arachnoid membrane
Dura mater:
- tough outermost sheet
Pia mater:
- delicate innermost layer
- lays directly over the surface of the cortex. It's very hard to dissect it off of the surface of the brain!
Arachnoid membrane:
- lies between the other two, is filled with cerebrospinal fluid (CSF)
- gets it name from its spiderweb appearance
CSF has two main functions:
- Acts as a shock absorber
- Provides an exchange medium between blood and brain
How does CSF flow through the ventricular system?
1.) Choroid plexus is a delicate layer that like the arachnoid membrane produces CSF
2.) The direction of flow of CSF begins with the lateral ventricle then on to the 3rd to the 4th ventricle
3.) CSF absorbed back into the circulatory system thru veins beneath the top of skull
List the ventricles of the brain.
- Right and left lateral ventricles (2)
- 3rd ventricle
- 4th ventricle
CT Scan can help visualize what?
- damaged tissue that results in memory speech and cognitive dysfunction.
Magnetic Resonance Imaging (MRI)
gives higher resolution images in three steps:
- Strong magnets cause protons in brain tissue to line up in parallel.
- A pulse of radio waves knocks protons over.
- Protons reconfigure themselves, emitting radio waves that differ by tissue density.
Positron emission tomography (PET)
- gives images of brain activity of:
- Uses radioactive chemicals injected into the bloodstream
- Identifies which brain regions contribute to specific functions
Functional MRI (fMRI)
- detects small changes in brain metabolism, like oxygen use, in active brain areas.
- fMRI can show how networks of brain structures collaborate.
The amount of oxygen available is measured indirectly, on the basis of blood flow or the state of hemoglobin in blood called the:
BOLD signal: blood-oxygen-level-dependent
Transcranial magnetic stimulation (TMS) briefly stimulates:
discrete cortical regions with magnets
Magnetoencephalography (MEG) measures:
the tiny magnetic fields given off by active neurons.
- Know the 5 perspectives used to explore the biology of behavior
1.) Description
2.) Evolution
3.) Development
4.) Mechanisms
5.) Application
What are the 3 approaches used to relate the brain to behavior?
Somatic Intervention
Behavioral Intervention
Correlation