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Lectures 1-5
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Why do we need epidemiology?
Identify trends in the public’s health (increase in colorectal cancer)
Provide advance warning of possible threats to public health (event based surveillance, sentinel surveillance, social media monitoring, wastewater testing)
Keep people healthy, prevent illness (screening, prevention, awareness, vaccination)
Maximize societal benefit, minimize burden (focus on prevention over treatment, cost effective prevention programs)
Reduce health disparities (build trust locally, widely promote all programs, tailoring programs and policies based on local data)
Early Epidemiologists - Hippocrates
Rejected the idea that illness was religious or supernatural, breaking with ancestral tradition
Recognized association of disease with place
Believed disease was a result of imbalance of the body’s “humors”
Creator of the Hippocratic Oath, modern version still used today
Early Epidemiologists - John Graunt
English statistician
Examined number and causes of death to identify variations in death according to sex, residence, season, and age
Miasma
Diseases caused by environmental factors such as contaminated water, foul air, and poor hygienic conditions
John Snow
Founder of epidemiology
Large cholera outbreak of London
At the time, water was distributed by two main suppliers
Traced the outbreak to one of the suppliers
Germ Theory - Louis Pasteur
Discovered that microorganisms could cause disease
Also studied fermentation and discovered pasteurization
Germ Theory - Robert Koch
Established 4 postulates for providing a microorganism causes disease
Be present in all cases of disease
Be isolated from disease patient
Cause disease when introduced to healthy host
Be isolated again from new host