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Definition:
Thermoregulation
Process of maintaining an internal temperature within a tolerable range.
What part of the brain determines the body's "set point" or normal temperature range?
hypothalamus
Endogenic VS Exogenic Heat Sources
- Endogenous = muscle activity, metabolism
- Exogenous = outside the body
What 4 methods are used to dispel heat from the body?
- Conduction: heat is conducted away from the body by contact with a cool surface
- Convection: heat is carried off the body by contact wit cooler, circulating air
- Evaporation: As liquid becomes vapor, the surface holding the liquid cools
- Radiation: heat moves from the body into the air w/out the assistance of circulating air
What are the 2 types of hyperthermia?
- Pyrogenic: caused by infection or inflammation; FEVER - the body will not try to cool itself
- Nonpyrogenic: not caused by infection or inflammation; the body will attempt to cool itself unless the thermoregulatory center is damaged
What are the 2 classifications of heatstroke?
- Exertional: occurs when an animal is worked or exercised in an environment it has not acclimated to; working dogs, competition dogs
- Nonexertional : animal cannot dissipate heat because of decreased airflow, lack of shade, no access to water, increase in temperature, or increase in humidity; dog tied out in the sun, locked in a car, confined in a kennel in an airplane cargo hold, etc.
What are predisposing factors of heatstroke?
Laryngeal paralysis
Brachycephalic airway
Tracheal collapse
Heart disease
Obesity
Effects of Heatstroke on the Body:
Cardiac
Vasodilation eventually occurs, causing venous pooling and decreased plasma volume/cardiac output, myocardial ischemia, and arrhythmia.
Effects of Heatstroke on the Body:
Pulmonary
- Noncardiogenic pulmonary edema
- Acute respiratory distress syndrome (ARDS)
- Decreased oxygen uptake by tissues = ischemia = myocardial damage = cardiovascular collapse
Effects of Heatstroke on the Body:
GI
- Liver damage
- GI barrier fails - bacterial translocation - SIRS/SEPSIS/MODS
- Widespread ischemia
Effects of Heatstroke on the Body:
Muscular
Rhabdomyolysis results from thermal injury to muscles; myoglobin is released, which is nephrotoxic = renal failure
Effects of Heatstroke on the Body:
Coagulation
Damaged endothelium = initial thrombosis followed by DIC
Effects of Heatstroke on the Body:
Neurologic
- Cell death = hemorrhage, cerebral edema
- Seizures
- Brain damage can occur at 105.8°F
Effects of Heatstroke on the Body:
Renal
- Decreased cardiac output and renal vasoconstriction = decreased renal perfusion; add dehydration = renal tubular necrosis
- Azotemia
Heatstroke Presentation includes ...
Presentation will depend on the animal’s compensation and the stage of shock!
- Altered mentation, collapse, ptyalism, V+/D+, panting
Heatstroke Diagnostics include ...
CBC, chem, coagulation panel, urinalysis, blood gas, blood smear, blood glucose, PCV/TS, ECG
Heatstroke Treatment includes ...
- # 1 treatment: cooling the patient
- Supplement oxygen
- Fluid resuscitation
- Serial blood pressure monitoring
- Blood products
- Dextrose
- Anti-arrhythmics
Primary VS Secondary Hypothermia
- Primary - due to cold exposure outside/water
- Secondary - disease, toxin, medications, anesthesia
Active VS Passive Rewarming for a Hypothermic P
- Passive - external covers (blankets etc)
- Active - external and core
What are the 2 types of active rewarming?
- External: (for moderate hypothermia = 82-90°F) transfer of heat from heat generating device - risk of burn
- Core: (for severe hypothermia= <82°F) pleural/peritoneal lavage, warmed O2, warmed IV fluids, warm enemas/bladder lavage
What are some complications for rewarming a hypothermic patient?
- Temp may still drop afterwards
- Rewarming shock - caused by vasodilation as a result of applied heat
- Heating pad burns