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True or False: The kidneys main function is to maintain the constancy of the body’s internal environment, aka HOMEOSTASIS
True
The kidney maintains the body’s homeostais by regulating the VOLUME and ___________ of the ECF (interstitial fluid)
a) mass
b) weight
c) composition
d) fluidity
c) composition
Which of the following does the kidney NOT manage when it comes to organic + inorganic compounds
a) intake
b) fertilization
c) production
d) excretion
e) consumption
b) fertilization
______________: the renal excretion of Na+, K+, Ca++, Mg++, H+, and HCO3^- balances the intake and excretion of these substances through other routes (ex: GI tract + skin)
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
a) regulation of blood IONIC composition + pH
______________: ex: urea + creatinine + uric acid (increased levels in blood = kidney failure)
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
b) excretion of organic WASTE products
______________: a) by way of RENIN formation + release (renin is then involved in activation the angiotensin-aldosterone pathway) b) by way of renal control of blood volume (ADH)
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
c) blood pressure regulation
______________: a) through the formation + release of the hormones ERYTHROPOIETIN which stimulates RBC production and b) CALCITROL, the active form of vitamin D
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
d) hormone production
______________: separately regulates loss of H2O + loss of solute
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
e) maintaining blood osmolarity
______________: involves H+ and HCO3^- balance
a) regulation of blood IONIC composition + pH
b) excretion of organic WASTE products
c) blood pressure regulation
d) hormone production
e) maintaining blood osmolarity
f) regulation of blood pH
f) regulation of blood pH
Kidney failure —> substances accumulating in the blood + ECF —> CHANGE in body’s internal environment —> ________ cell function and ________
a) decreased, death
b) increased, death
a) decreased, death
____________: positions on the upper POSTERIOR wall of the abdominal cavity (T12-L3)
a) kidneys
b) gallbladder
c) liver
d) heart
a) kidneys
____________: located between the muscles of the back and the peritoneal cavity
a) kidneys
b) gallbladder
c) liver
d) heart
a) kidneys
True or false: The kidneys are RETROPERITONEAL
True
True or False: Both kidneys are capped by an adrenal gland (suprarenal gland)
True
True or False: The kidneys can be surgically approached through the posterior body wall without opening the peritoneal cavity
True
True or False: The right kidney is lower than the left because the liver pushes the right kidney down
True
True or False: The left kidney is lower than the right because the liver pushes the left kidney down
False
The kidney is bean shaped, with a _________ lateral border and _______ medial border
a) concave, convex
b) concave, concave
c) convex, convex
d) convex, concave
d) convex, concave
____________: indentation on the MEDIAL border through which most structures entered (ex: renal artery) or leave (ex: renal vein, ureter) the kidney
a) hilum
b) renal sinus
c) renal capsule
d) adipose capsule
e) renal fasciia
a) hilum
____________: internal space the hilum opens into which contains the renal vessels + the renal pelvis + calyces
a) hilum
b) renal sinus
c) renal capsule
d) adipose capsule
e) renal fasciia
b) renal sinus
____________: innermost layer; directly covers the kidney; fibrous
a) hilum
b) renal sinus
c) renal capsule
d) adipose capsule
e) renal fasciia
c) renal capsule
____________: mass of perineal fat surrounding the renal capsule
a) hilum
b) renal sinus
c) renal capsule
e) renal fasciia
d) adipose capsule
____________: surrounds the adipose capsule, completely enclosing + anchoring the kidney to the posterior abdominal wall
a) hilum
b) renal sinus
c) renal capsule
d) adipose capsule
e) renal fasciia
e) renal fasciia
The renal parenchyma is divisible into ____ regions
a) 1
b) 2
c) 3
d) 4
b) 2
________ = 3 parts/divisions if including the sinus
a) internal kidney
b) the CORTEX
c) the MEDULLA
a) internal kidney
__________: the lighter outer layer (just deep to the renal capsule)
a) internal kidney
b) the CORTEX
c) the MEDULLA
b) the CORTEX
__________: divided into an outer “cortical zone” and inner “juxtamedullary zone” (extensions of the cortex (renal columns) extend into the medulla between the “pyramids”)
a) internal kidney
b) the CORTEX
c) the MEDULLA
b) the CORTEX
__________: deep to the cortex; formed by several (8-18) triangular renal pyramids
a) internal kidney
b) the CORTEX
c) the MEDULLA
c) the MEDULLA
__________: Renal pyramids are separated from one another by the “columns”; contain blood vessels that supply the cortex + medulla + 1/2 each adjacent column
a) internal kidney
b) the CORTEX
c) the MEDULLA
c) the MEDULLA
The pyramids of the kidney are oriented with the broad bases covered by cortex and their tips, the _________, projected toward the renal pelvis
a) papillae
b) renal lobe
c) the cortex
d) the medulla
a) papillae
___________: one pyramid + overlying cortex + ½ each adjacent column
a) papillae
b) renal lobe
c) the cortex
d) the medulla
b) renal lobe
__________: is funnel-shapped with a papilla projecting into it (around 8-18 per kidney)
a) minor calyces
b) major calyces
c) the renal pelvis
a) minor calyces
__________: is formed by the fusion of several minor calyces (around 3 per kidney)
a) minor calyces
b) major calyces
c) the renal pelvis
b) major calyces
__________: formed by the fusion of the major calyces = the expanded upper part of the ureter
a) minor calyces
b) major calyces
c) the renal pelvis
c) the renal pelvis
___________: the functional units of the kidneys where urine is FORMED, around 1 million per kidney
a) nephrons
b) cortical nephron
c) juxtamedullary nephrons
a) nephrons
___________: 80-85% of the nephrons in the kidney; have short “loops of Henle” which descend only as far as the outer medulla
a) nephrons
b) cortical nephron
c) juxtamedullary nephrons
b) cortical nephron
__________: corpuscles located at the junction of the cortex + medulla of the kidney; have LONG “loops of henle” which penetrate deep into the medulla and sometimes reach the top of the renal papillae
a) nephrons
b) cortical nephron
c) juxtamedullary nephrons
c) juxtamedullary nephrons
___________: these nephrons are important in the counter-current system by which the kidneys CONCENTRATE urine
a) nephrons
b) cortical nephron
c) juxtamedullary nephrons
c) juxtamedullary nephrons
___________: part of the nephron; a network of parallel CAPILLARIES (20-40 capillary loops)
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
___________: part of nephron; in epithelial lined tube with various regions that differ from one another anatomically (EPITHELIAL variations)
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
b) a renal tubule
___________: Made up of Bowman’s capsule, proximal convoluted tubule, loop of Henle, distal convoluted tubule, “collecting tubule”
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
b) a renal tubule
The _________ is made up of the glomerular CAPSULE/Bowman’s capsule + the glomerulus
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
d) renal corpuscle
_____________: makes up the renal corpuscle; a double walled cup formed by the proximal end of the renal tubule
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
c) the glomerular capsule/bowman’s capsule
____________: makes up the renal corpuscle; a tuft of capillary loops which protrudes into the Bowman’s capsule; located in the kidney’s cortex
a) the glomerulus
b) a renal tubule
c) the glomerular capsule/bowman’s capsule
d) renal corpuscle
a) the glomerulus
____________: a process occurring in the CORPUSCLES that is important in urine production; movement of molecules out of blood and into filtrate
a) cortical filtration
b) renal filtration
c) corpuscle filtration
d) glomerular filtration
d) glomerular filtration
___________: occurs when some of the blood plasma (except for protein) passes out of the glomerular capillaries and exits the space (capsular space) between the inner + outer layers of the capsule
a) cortical filtration
b) renal filtration
c) corpuscle filtration
d) glomerular filtration
d) glomerular filtration
The process of glomerular filtration creates a fluid called glomerular _______
a) urine
b) filtrate
c) fluid
d) waste
b) filtrate
The ______________ is made up of 2 layers, an outer/parietal layer and an inner/visceral layer
a) the glomerulus
b) a renal tubule
c) bowman’s capsule
d) renal corpuscle
c) bowman’s capsule
____________: part of Boman’s capsule; made up of simple squamous epithelias
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
a) outer/parietal layer of capsule
____________: part of Bowman’s capsule; composed of specialized cells for the filtration barrier
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
b) inner/visceral layer of capsule
____________: have several processes that pranch to form 3rd degree processes
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
c) podocytes
____________: aka foot processes or 3rd degree processes; adheres to basal lamina (basement membrane) covering the capillary endothelilum
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
d) pedicles
__________:a network of small clefts between them, also known as filtration slits, created when the foot processes of one podocyte interdigitate with those of adjacent podocytes
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
e) slit pores
__________: a thin slit membrane extends between foot processes barrier restricting the passage of some molecules through slits
a) outer/parietal layer of capsule
b) inner/visceral layer of capsule
c) podocytes
d) pedicles
e) slit pores
e) slit pores
_________: endothelium formed by a single layer of squamouse cells; contains small pores (fenestrated capillaries —> permeable!)
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
b) glomerular capillaries
_________: the separation beteween the blood in the glomerular capillaries from the capsular space
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
c) filtration barrier membrane
_________:
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
c) filtration barrier membrane
_________: consists of 3 layers
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
c) filtration barrier membrane
Which of the following is NOT a layer in the filtration barrier membrane?
a) the podocyte layer
b) the fenestrated endothelium
c) the basal lamina (basement membrane of capillary endothelium)
d) the slit membranes that cover the filtration slits
a) the podocyte layer
Many substances are able to pass through the __________, substances that are less than 3nm in diameter
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
c) filtration barrier membrane
__________: consist of most substances present in the plasma EXCEPT most plasma PROTEINS
a) slit pores
b) glomerular capillaries
c) filtration barrier membrane
d) glomerular filtrate
d) glomerular filtrate
True or False: Proteins are too large to penetrate through the filtrations barrier
True
What is the correct order of the speed of molecules of the same size through the filtration barrier?
a) (-) molecule > (+) molecule > neutral molecule
b) (+) molecule > (-) molecule > neutral molecule
c) (-) molecule > neutral molecule > (-) molecule
d) (+) molecule > neutral molecule > (-) molecule
d) (+) molecule > neutral molecule > (-) molecule
_________ charged glycoproteins are associated with the filtration barrier and influence the movement of molecules across the barrier
a) positively (+)
b) negatively (-)
c) neutral
b) negatively (-)
________ to the filtration membrane can be caused by kidney inflammation or trauma
a) damage
b) albuminuria
c) hematuria
d) nitricuria
a) damage
________: proteinuria; condition when albumin is in the urine
a) damage
b) albuminuria
c) hematuria
d) nitricuria
b) albuminuria
________: condition when blood (RBCs) are in the urine
a) damage
b) albuminuria
c) hematuria
d) nitricuria
c) hematuria
____________: part of urinary system for FILTRATION
a) Bowman’s Capsule
b) Renal Tubule
c) Proximal convoluted tubule
d) Loop of Henle
a) Bowman’s Capsule
____________: part of urinary system for REABSORPTION
a) Bowman’s Capsule
b) Renal Tubule
c) Proximal convoluted tubule
d) Loop of Henle
b) Renal Tubule
_______________: the region of the renal tubule beyond the glomerular capsule whose lumen is continuous with the capsular space
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
a) proximal convoluted tubule
_______________: located in cortex; twisted; large surface area for reabsorption + secretion
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
a) proximal convoluted tubule
_______________: wall is a single layer of columnar cells with MICROVILLLI that extend into the lume (brush border) —> allows for more reabsorption
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
a) proximal convoluted tubule
_______________: contains a descending and ascending limb
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
b) loop of henle
_______________: the highly coiled region beyond the distal straight tubule
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
c) distal convoluted tubule
_______________: wall is a single layer of cuboidal cells with few microvilli
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
c) distal convoluted tubule
_______________: a large tubule in which distal convoluted tubules of SEVERAL nephrons empty inot
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
d) collecting tubule
_______________: passes through a medullary renal pyramid —> joining together of adjacent collecting tubules to form larger ducts (PAPILLARY DUCTS) that open on the papilla —> minor calyx
a) proximal convoluted tubule
b) loop of henle
c) distal convoluted tubule
d) collecting tubule
d) collecting tubule
____________: part of each loop that descends into the medulla
a) loop of henle
b) descending limb
c) ascending limb
d) collecting tubule
b) descending limb
____________: wall is thin squamous epithelium; thin segment of the loop
a) loop of henle
b) descending limb
c) ascending limb
d) collecting tubule
b) descending limb
____________: formed in the medullar by hairpin turn the loop takes; passes out of medulla —> cortex
a) loop of henle
b) descending limb
c) ascending limb
d) collecting tubule
c) ascending limb
____________: wall is cuboidal cells (in thick areas) and squamous cells (in thin)
a) loop of henle
b) descending limb
c) ascending limb
d) collecting tubule
c) ascending limb
True or False: In juxtamedullary nephrons, the thick segment does not begin until the upper portion of the ascending limb
True
Each kidney receives a ________ = a major branch from the descending aorta
a) renal artery
b) renal vein
c) kidney artery
d) kidney vein
a) renal artery
The kidneys receive around _____ of the total cardiac output —> 1.1 L/min of blood passing through the two kidneys
a) 5%
b) 10%
c) 15%
d) 20%
d) 20%
True or false: Most of the blood going to the kidneys is for kidney cell nutrition
False
True or false: Little of the blood going to the kidneys is used for kidney cell nutrition
True
True or false: The purpose of large blood flow to the kidneys is to maintain blood homeostasis
True
True or false: Shortly after entering the hilus, the renal artery divides into separate arteries and capillaries
True
_________: travel between the pyramids (lobes) to the arcuate arteries
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
a) interlobar arteries
_________: arching branches given off by the interlobar arteris at the bases of the pyramids (cortex-medula junction); runs parallel to the kidney surface —> interlobular arteries
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
b) arcuate arteries
_________: small branches given off at intervals by the arcuate arteries + which travel through the cortex toward the kidney surface —> afferent arterioles
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
c) interlobular arteries
_________: divisions of the interlobular arteries; each supplies a renal corpuscle to form the capillary network (glomerulus)
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
d) afferent arterioles
_________: glomerular filtrate formed here —> efferent arteriole
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
d) afferent arterioles
_________: blood LEAVES the glomerulus through this arteriole —> peritubular capillaries
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
e) efferent arteriole
_________: divisions of the efferent arterioles which forms networks surrounding the renal tubules
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
g) vasa recta
f) peritubular capillaries
_________: thin-waled vessels which extend from the efferent arteriole of the juxtamdeullary nephrons to supply the loop of Henle + collecting tubules in the medulla
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
g) vasa recta
_________: important role in URINE CONCENTRATION
a) interlobar arteries
b) arcuate arteries
c) interlobular arteries
d) afferent arterioles
e) efferent arteriole
f) peritubular capillaries
g) vasa recta
g) vasa recta
__________ or __________ empty into interlobular veins —> —> renal veins
a) peritubular capillaries, efferent arteriole
b) peritubular capillaries, vasa recta
c) vasa recta, efferent arteriole
d) afferent arteriole, efferent arteriole
b) peritubular capillaries, vasa recta
True or False: Veins follow course of arteries with the same names
True or False: Veins follow course of arteries with the same names
True or False: Blood flows through 2 sequential series of capillary beds —> glomerulus and peritubular capillaries
True