MED QUIZ 1 (3rd Gen Seizure Meds)

BLACK BOX warning for Everolimus

Immunosuppression, infections, malignancy risk

Everolimus is used to treat

Tuberous sclerosis complex related seizures

Tuberous sclerosis complex is a __________ disorder causing __________ in multiple organs, including the brain

Genetic, benign tumors

Major side effects for Everolimus

Stomatitis, infection, hyperlipidemia, delayed wound healing

Nurse responsibilities for a patient taking Everolimus

Monitor CBC, lipids, renal/liver function

Patient teaching when taking Everolimus

Avoid live vaccines, report mouth ulcers or signs of infection

When you think of Everolimus, think

Immunosuppression

BLACK BOX warning for Cenobamate

DRESS syndrome

DRESS syndrome stands for

Drug Reaction with Eosinophilia and Systemic Symptoms

Major side effects of Cenobamate

Major fatigue, dizziness, QT shortening, liver enzyme changes

Nurse responsibilities for a patient taking Cenobamate

Monitor for rash/systemic illness, check LFTs, EKG

Patient teaching while taking Cenobamate

Report rash, fever, swollen lymph nodes, taper slowly

When you think of Cenobamate, think

DRESS

BLACK BOX warning for Fenfluramine

Valvular heart disease and pulmonary arterial hypertension

fenfluramine is used for

Dravet Syndrome

Dravet Syndrome is rare __________ epilepsy beginning in ___________

Genetic, infancy (6-12m)

What are the major side effects of Fenfluramine?

Decrease appetite, weight loss, chronic fatigue

Nurse responsibilities for a patient taking Fenfluramine

Baseline and periodic echocardiograms, monitor for dyspnea and edema

Patient teaching when taking Fenfluramine

Report SOB, swelling, Palpations

When you think of Fenfluramine, think

Dravet, heart/lung risk, Echo needed

Ganaxolone is a

Neurosteroid

Stiripentol can cause issues with what blood work?

CBC

Zonisamide can cause

Kidney stones and sulfa allergy

Tiagabine increases

GABA